Psychiatric disorders are characterized by sex differences in their prevalence,
symptomatology and treatment response. Animal models have been widely employed for …

Many aspects of brain functioning exhibit important sex differences that affect behavior,
mental health and mental disorders. However, most translational neuroscience research …

Many stress‐related mental disorders, including depression and post‐traumatic stress
disorder occur more often in women than in men. While social and cultural factors certainly …

In clinical populations, sex differences in disease prevalence, symptoms and outcome have
been established. Despite this, female rats are frequently omitted from preclinical research; …

Clinical studies have shown that women are more susceptible to depression than men. Sex
differences in depression have been associated with social, cultural, as well as biological …

This chapter critically discusses the process of developing, validating, and working with
animal models relevant to psychiatric disorders. A model is defined as any experimental …

Mood disorders are devastating, often chronic illnesses characterized by low mood, poor
affect, and anhedonia. Notably, mood disorders are approximately twice as prevalent in …

Mental disorders are a significant cause of disability worldwide. They profoundly affect
individuals' well-being and impose a substantial financial burden on societies and …

Epidemiological sex differences in anxiety disorders and major depression are well
characterized. Yet the circuits and mechanisms that contribute to these differences are …

Sex differences have been observed across many psychiatric diseases, especially mood
disorders. For major depression, the most prevalent psychiatric disorder, females show a …