Investigation on the effect of Piezo1 on periodontal tissue and periodontal ligament
fibroblasts (PDLFs) under mechanical stress and the underlying mechanism. The …

Objective: To evaluate the function of Piezo1, an evolutionarily conserved mechanically
activated channel, in periodontal ligament (PDL) tissue homeostasis under compressive …

The identification of mechanosensitive ion channels and their importance in innate immunity
provides new starting points to elucidate the molecular mechanisms of orthodontic tooth …

Orthodontic tooth movement (OTM) is a process depending on the remodeling of periodontal
tissues surrounding the roots. Orthodontic forces trigger the conversion of mechanical stimuli …

The effect of compression force on periodontal ligament (PDL) plays a critical role in
orthodontic tooth movement. However, little is known about this effect on apoptosis and the …

Objectives The aim of this research was to investigate the functions of Piezo channels in
dentin defect, including mechanical signalling and odontoblast responses. Methods Rat …

Objectives Orthodontic mechanical force on the periodontal ligament induces extracellular
adenosine triphosphate (ATP) release. However, mechanosensitive molecules have not …

Introduction The mechanosensitive ion channel, Piezo1, is responsible for transducing
mechanical stimuli into intracellular biochemical signals and has been identified within …

Human Periodontal Ligament Fibroblasts (hPDLF), as part of the periodontal apparatus,
modulate inflammation, regeneration and bone remodeling. Interferences are clinically …

Objective Orthodontic tooth movement (OTM) is based on alveolar bone remodeling under
mechanical force. In 2010, Piezo1 was identified as a mechanosensitive ion channel that is …