The cytotoxic and apoptotic effects of turmeric (Curcuma longa) on colon cancer have been
well documented but specific structural modifications of curcumin have been shown to …

Background Colorectal carcinoma is one of the major causes of morbidity and mortality in
the Western World. Novel therapeutic approaches are needed for colorectal carcinoma …

Abstract (E)− 1-(3′-fluoro-[1, 1′-biphenyl-3-yl)− 3-(3-hydroxy-4-methoxyphenyl) prop-2-en-
1-one)(MC37), a novel mono-carbonyl curcumin analog, was previously synthesized in our …

Curcumin and its chalcone derivatives have well‐known, explicit biological antitumor
properties, such as instance antiproliferative and apoptotic effects via multiple molecular …

Curcumin is a potential anticancer drug with poor bioavailability, which limits its clinical use
as a therapeutic agent. The aim of this study was a preliminary evaluation of the curcumin …

Curcumin has poor in vivo absorption and bioavailability, highlighting a need for new
curcumin analogues with better characteristics in these aspects. The aim of this study is to …

Sixty-one curcumin-related compounds were synthesized and evaluated for their anticancer
activity toward cultured prostate cancer PC-3 cells, pancreas cancer Panc-1 cells and colon …

Colorectal cancer (CRC) is the third most common type of cancer worldwide and a leading
cause of cancer death. According to the Malaysian National Cancer Registry Report 2012 …

Gastric cancer is one of the most frequent malignant tumors in the world. The majority of
patients are diagnosed with metastatic gastric cancer, which has a low survival rate. These …

This study aimed to evaluate the efficacy of Chemoprevention Curcumin Analog-1.1 (CCA-
1.1) and Pentagamavunone-1 (PGV-1) in vivo and in vitro in colorectal cancer model. CCA …