Actin cortex architecture regulates cell surface tension

P Chugh, AG Clark, MB Smith, DAD Cassani… - Nature cell …, 2017 - nature.com
Animal cell shape is largely determined by the cortex, a thin actin network underlying the
plasma membrane in which myosin-driven stresses generate contractile tension. Tension …

The actin cortex at a glance

P Chugh, EK Paluch - Journal of cell science, 2018 - journals.biologists.com
Precisely controlled cell deformations are key to cell migration, division and tissue
morphogenesis, and have been implicated in cell differentiation during development, as well …

[HTML][HTML] Extent of myosin penetration within the actin cortex regulates cell surface mechanics

BA Truong Quang, R Peters, DAD Cassani… - Nature …, 2021 - nature.com
In animal cells, shape is mostly determined by the actomyosin cortex, a thin cytoskeletal
network underlying the plasma membrane. Myosin motors generate tension in the cortex …

[PDF][PDF] Stresses at the cell surface during animal cell morphogenesis

AG Clark, O Wartlick, G Salbreux, EK Paluch - Current Biology, 2014 - cell.com
Cell shape is determined by cellular mechanics. Cell deformations in animal cells, such as
those required for cell migration, division or epithelial morphogenesis, are largely controlled …

Mechanics of the cellular actin cortex: From signalling to shape change

M Kelkar, P Bohec, G Charras - Current opinion in cell biology, 2020 - Elsevier
The actin cortex is a thin layer of actin, myosin and actin-binding proteins that underlies the
membrane of most animal cells. It is highly dynamic and can undergo remodelling on …

[PDF][PDF] Monitoring actin cortex thickness in live cells

AG Clark, K Dierkes, EK Paluch - Biophysical journal, 2013 - cell.com
Animal cell shape is controlled primarily by the actomyosin cortex, a thin cytoskeletal
network that lies directly beneath the plasma membrane. The cortex regulates cell …

[PDF][PDF] Precise tuning of cortical contractility regulates cell shape during cytokinesis

N Taneja, MR Bersi, SM Baillargeon, AM Fenix… - Cell reports, 2020 - cell.com
The mechanical properties of the actin cortex regulate shape changes during cell division,
cell migration, and tissue morphogenesis. We show that modulation of myosin II (MII) …

Cell shape and substrate stiffness drive actin-based cell polarity

M Gupta, BL Doss, L Kocgozlu, M Pan, RM Mège… - Physical Review E, 2019 - APS
A general trait of living cells is their ability to exert contractile stresses on their surroundings
and thus respond to substrate rigidity. At the cellular scale, this response affects cell shape …

Control of cortical rigidity by the cytoskeleton: emerging roles for septins

J Gilden, MF Krummel - Cytoskeleton, 2010 - Wiley Online Library
The cortex is the outermost region of the cell, comprising all of the elements from the plasma
membrane to the cortical actin cytoskeleton that cooperate to maintain the cell's shape and …

[PDF][PDF] The actin cortex: a bridge between cell shape and function

KJ Chalut, EK Paluch - Developmental cell, 2016 - cell.com
The cortical actin network controls many animal cell shape changes by locally modulating
cortical tension. Recent work has provided insight into cortex components and regulators …