Melatonin alleviates Neuroinflammation and metabolic disorder in DSS‐induced depression rats

W Lv, C Liu, L Yu, J Zhou, Y Li, Y Xiong… - Oxidative medicine …, 2020 - Wiley Online Library
There is a bidirectional relationship between inflammatory bowel disease (IBD) and
depression/anxiety. Emerging evidences indicate that the liver may be involved in …

Melatonin Ameliorates Corticosterone‐Mediated Oxidative Stress‐Induced Colitis in Sleep‐Deprived Mice Involving Gut Microbiota

T Gao, Z Wang, J Cao, Y Dong… - Oxidative medicine and …, 2021 - Wiley Online Library
Background. Inflammatory bowel disease (IBD) is a result of a complex interplay, making
development of a specific treatment a challenging task. Corticosterone was considered a …

[HTML][HTML] Melatonin promotes gut anti-oxidative status in perinatal rat by remodeling the gut microbiome

X Yi, R Cai, W Shaoyong, G Wang, W Yan, Z He, R Li… - Redox biology, 2023 - Elsevier
Gut health is important for nutrition absorption, reproduction, and lactation in perinatal and
early weaned mammals. Although melatonin functions in maintaining circadian rhythms and …

[HTML][HTML] Gut microbiota-derived metabolites mediate the neuroprotective effect of melatonin in cognitive impairment induced by sleep deprivation

X Wang, Z Wang, J Cao, Y Dong, Y Chen - Microbiome, 2023 - Springer
Background Sleep loss is a serious global health concern. Consequences include memory
deficits and gastrointestinal dysfunction. Our previous research showed that melatonin can …

[HTML][HTML] Jasmine tea attenuates chronic unpredictable mild stress-induced depressive-like behavior in rats via the gut-brain axis

Y Zhang, J Huang, Y Xiong, X Zhang, Y Lin, Z Liu - Nutrients, 2021 - mdpi.com
The number of depressed people has increased worldwide. Dysfunction of the gut
microbiota has been closely related to depression. The mechanism by which jasmine tea …

Curcumin Alleviates DSS‐Induced Anxiety‐Like Behaviors via the Microbial‐Brain‐Gut Axis

F Zhang, Y Zhou, H Chen, H Jiang… - Oxidative medicine …, 2022 - Wiley Online Library
The anxiety and depression caused by inflammatory bowel diseases (IBD) are known to
greatly affect the mental health of patients. The mechanism of psychiatric disorders caused …

Melatonin-mediated MT2 attenuates colitis induced by dextran sodium sulfate via PI3K/AKT/Nrf2/SIRT1/RORα/NF-κB signaling pathways

T Gao, T Wang, Z Wang, J Cao, Y Dong… - International …, 2021 - Elsevier
Background Inflammatory bowel disease (IBD) is an inflammatory response relative chronic
disease in the intestinal tract. Our previous study demonstrated melatonin exerts an …

Role of melatonin in sleep deprivation‐induced intestinal barrier dysfunction in mice

T Gao, Z Wang, Y Dong, J Cao, R Lin… - Journal of pineal …, 2019 - Wiley Online Library
Intestinal diseases caused by sleep deprivation (SD) are severe public health threats
worldwide. This study focuses on the effect of melatonin on intestinal mucosal injury and …

[HTML][HTML] Gut microbiota dysbiosis induced by decreasing endogenous melatonin mediates the pathogenesis of Alzheimer's disease and obesity

B Zhang, T Chen, M Cao, C Yuan, RJ Reiter… - Frontiers in …, 2022 - frontiersin.org
Lifestyle choices, external environment, aging, and other factors influence the synthesis of
melatonin. Although the physiological functions of melatonin have been widely studied in …

Melatonin alleviates intestinal injury, neuroinflammation and cognitive dysfunction caused by intestinal ischemia/reperfusion

B Yang, LY Zhang, Y Chen, YP Bai, J Jia… - International …, 2020 - Elsevier
Intestinal ischemia/reperfusion (I/R) can cause multiple organ damage with extremely high
morbidity and mortality. Melatonin has anti-inflammatory, anti-oxidative and anti-apoptotic …