Whilst effective antiretroviral therapy is protective against the more severe forms of HIV-
associated brain disease, there remains a large burden of clinically symptomatic cognitive …

As our understanding of changes to the neurological system has improved, it has become
clear that patients who have contracted human immunodeficiency virus type 1 (HIV-1) can …

Combination antiretroviral therapy (CART) has proven to effectively suppress systemic HIV
burden, however, poor penetration into the central nervous system (CNS) provides …

The development of novel antiretroviral treatments has led to a significant turning point in the
fight against HIV. Although therapy leads to virologic suppression and prolonged life …

Highly active antiretroviral treatment has led to unprecedented efficacy and tolerability in
people living with HIV. This effect was also observed in the central nervous system with the …

People living with HIV are affected by the chronic consequences of neurocognitive
impairment (NCI) despite antiretroviral therapies that suppress viral replication, improve …

Abstract Purpose of Review: Neurologic complications of HIV infection are unfortunately
common, even in the era of effective antiretroviral treatment (ART). The consulting …

Human immunodeficiency virus type 1 (HIV) infection presently affects more that 40 million
people worldwide, and is associated with central nervous system (CNS) disruption in at least …

Highly actively antiretroviral therapy may need to be optimized in patients with HIV-
associated cognitive impairment to achieve maximal central nervous system penetration; …

Despite the fact that neurons are rarely infected by the human immunodeficiency virus (HIV),
neuronal loss is common in patients with HIV infection, likely due to the effects of viral …