Background and Purpose: Ciprofol (HSK3486), a novel 2, 6-disubstituted phenol derivative,
is a new intravenous anesthetic compound with a similar chemical structure to propofol …

Introduction: Icariin, a major component of Epimedium species and a mild
phosphodiesterase 5 (PDE-5) inhibitor, was evaluated for the prevention of myocardial …

Aims Cyclophosphamide (CYP) is a potent anticancer agent with well-known cardiotoxicity
that limits its clinical applications. Cilostazol is a vosodilating drug, showing a …

The present study was aimed at investigating the effect of amifostine on myocardial
ischemia/reperfusion (I/R) injury of mice and H9c2 cells cultured with TBHP (tert‐butyl …

Icariin, a major component of Epimedium species, was evaluated using isoproterenol (ISO)-
induced cardiotoxicity in Wistar rats. Rats were treated with icariin at the doses of 1, 5, and …

Piperazine ferulate (PF) has been reported to protect cardiac from ischemia/reperfusion
injury to achieve myocardial protection. NLRP3 inflammasome activation–mediated …

The role of oxidative injury and inflammatory response in cardiovascular diseases and heart
failure has been well-acknowledged. This study evaluated the protective effect of …

Phytomedicine has shown a promising potential for the prevention of cardiovascular system
diseases and disorders. This study aimed to evaluate protective effect of ergosterol (ER) on …

Alleviating cardiac dysfunction improves the prognosis of heart failure patients. Lycorine is
an alkaloid with several beneficial biological properties. Here, we used mice to evaluate the …

Oxidative stress plays a critical role in the progression of myocardial injury. Increasing
evidence suggests that hiruidin can treat patients with cardio-injury. However, the …