The mitochondrial respiration signature of the bovine blastocyst reflects both environmental conditions of development as well as embryo quality

J Kurzella, D Miskel, F Rings, E Tholen, D Tesfaye… - Scientific Reports, 2023 - nature.com
The major limitation of the widespread use of IVP derived embryos is their consistent
deficiencies in vitality when compared with their ex vivo derived counterparts. Although …

Mitochondrial bioenergetic profiles of warmed bovine blastocysts are typically altered after cryopreservation by slow freezing and vitrification

J Kurzella, D Miskel, F Rings, E Tholen, D Tesfaye… - Theriogenology, 2024 - Elsevier
The widespread use of cryopreserved in vitro produced (IVP) bovine embryos is limited due
to their low post-warming viability compared to their ex vivo derived counterparts. Therefore …

Effect of serum on the mitochondrial active area on developmental days 1 to 4 in in vitro-produced bovine embryos

M Crocco, RH Alberio, L Lauria, MI Mariano - Zygote, 2011 - cambridge.org
Certain morphological changes at the subcellular level caused by the current techniques for
in vitro embryo production seem to affect mitochondria. Many of these, including …

Mitochondrial activity and morphology in developing porcine oocytes and pre‐implantation non‐cultured and cultured embryos

M Romek, B Gajda, M Rolka… - … in Domestic Animals, 2011 - Wiley Online Library
Contents Mitochondria are important determinants of developmental competence for
oocytes and embryos owing to their central role in cellular metabolism, yet mitochondrial …

Influence of bovine serum albumin and fetal bovine serum supplementation during in vitro maturation on lipid and mitochondrial behaviour in oocytes and lipid …

M Del Collado, NZ Saraiva, FL Lopes… - Reproduction …, 2016 - CSIRO Publishing
Proper oocyte maturation is crucial for subsequent embryo development; however, oocyte
mitochondrial and lipid-droplet behaviour are still poorly understood. Although excessive …

Mitochondrial maturation in the trophectoderm and inner cell mass regions of bovine blastocysts

Y Hayashi, S Saito, H Bai, M Takahashi, M Kawahara - Theriogenology, 2021 - Elsevier
Cellular differentiation induces various morphological changes, including elongation, in
mitochondria. Preimplantation embryos have round-shaped mitochondria, characteristic of …

[HTML][HTML] The metabolic profile of bovine blastocysts is affected by in vitro culture system and the pattern of first zygotic cleavage

D Lechniak, E Sell-Kubiak, E Warzych - Theriogenology, 2022 - Elsevier
Time lapse monitoring (TLM) is a commercial system of individual embryo culture based on
the well-of-the-well system. It allows for collecting a panel of intrinsic parameters of special …

Oxygen concentration alters mitochondrial structure and function in in vitro fertilized preimplantation mouse embryos

M Belli, L Zhang, X Liu, A Donjacour… - Human …, 2019 - academic.oup.com
STUDY QUESTION Does the oxygen concentration in the culture medium [either physiologic
(5%) or atmospheric (20%)] affect mitochondrial ultrastructure and function in …

Metabolic regulation during early embryo development

PJ McKeegan - 2015 - etheses.whiterose.ac.uk
The preimplantation embryo must satisfy dynamic changes in energy demand during
development to the blastocyst stage. Energy is provided through regulated metabolic …

Mitochondrial reactive oxygen species regulate mitochondrial biogenesis in porcine embryos

M Kageyama, J Ito, K Shirasuna… - … of Reproduction and …, 2021 - jstage.jst.go.jp
The number of mitochondria in blastocysts is a potential marker of embryo quality. However,
the molecular mechanisms governing the mitochondrial number in embryos are unclear …