Cardiac troponin level elevations not related to acute coronary syndromes

E Giannitsis, HA Katus - Nature reviews cardiology, 2013 - nature.com
Over the past 2 decades, cardiac troponins (cTn) have emerged as the preferred biomarkers
for the noninvasive detection of myocardial injury. In conjunction with typical clinical findings …

Troponin elevation in coronary vs. non-coronary disease

S Agewall, E Giannitsis, T Jernberg… - European heart …, 2011 - academic.oup.com
Acute myocardial infarction is defined as myocardial cell death due to prolonged myocardial
ischaemia. Cardiac troponins (cTn) are the most sensitive and specific biochemical markers …

Possible mechanisms behind cardiac troponin elevations

O Hammarsten, J Mair, M Möckel, B Lindahl, AS Jaffe - Biomarkers, 2018 - Taylor & Francis
Cardiac-specific troponins are elevated in blood following cardiac injury and are the
preferred diagnostic biomarkers when acute myocardial infarction is suspected clinically …

High-sensitive troponin T measurements: what do we gain and what are the challenges?

R Twerenbold, A Jaffe, T Reichlin, M Reiter… - European heart …, 2012 - academic.oup.com
Cardiac troponin (cTn) I and T are structural proteins unique to the heart. Detection of cTn in
peripheral blood indicates cardiomyocyte damage. As acute myocardial infarction (AMI) is …

Cardiac troponins: from myocardial infarction to chronic disease

KC Park, DC Gaze, PO Collinson… - Cardiovascular …, 2017 - academic.oup.com
Elucidation of the physiologically distinct subunits of troponin in 1973 greatly facilitated our
understanding of cardiac contraction. Although troponins are expressed in both skeletal and …

Increases of cardiac troponin in conditions other than acute coronary syndrome and heart failure

WE Kelley, JL Januzzi, RH Christenson - Clinical chemistry, 2009 - academic.oup.com
Background: Although cardiac troponin (cTn) is a cornerstone marker in the assessment and
management of patients with acute coronary syndrome (ACS) and heart failure (HF), cTn is …

Cardiac troponin elevation in patients without a specific diagnosis

KM Eggers, T Jernberg, B Lindahl - Journal of the American College of …, 2019 - jacc.org
Background: Cardiac troponin (cTn) elevation is a common finding in acutely admitted
patients, even in the absence of acute coronary syndrome. In some of these patients, no …

Troponin elevation in conditions other than acute coronary syndromes

A Tanindi, M Cemri - Vascular health and risk management, 2011 - Taylor & Francis
Acute coronary syndromes comprise a large spectrum of clinical conditions ranging from
unstable angina pectoris to acute ST-elevation myocardial infarction. Chest pain is usually …

Application of cardiac troponin in cardiovascular diseases other than acute coronary syndrome

KM Eggers, B Lindahl - Clinical chemistry, 2017 - academic.oup.com
BACKGROUND Increased cardiac troponin concentrations in acute coronary syndrome
(ACS) identify patients with ongoing cardiomyocyte necrosis who are at increased risk …

Cardiac biomarkers of acute coronary syndrome: from history to high-sensitivity cardiac troponin

P Garg, P Morris, AL Fazlanie, S Vijayan… - Internal and emergency …, 2017 - Springer
The role of cardiac troponins as diagnostic biomarkers of myocardial injury in the context of
acute coronary syndrome (ACS) is well established. Since the initial 1st-generation assays …