Molecular mechanisms linking oxidative stress and diabetes mellitus

H Yaribeygi, T Sathyapalan, SL Atkin… - … medicine and cellular …, 2020 - Wiley Online Library
Type 2 diabetes mellitus (T2DM) is the most prevalent metabolic disorder characterized by
chronic hyperglycemia and an inadequate response to circulatory insulin by peripheral …

Molecular Events Linking Oxidative Stress and Inflammation to Insulin Resistance and β‐Cell Dysfunction

KN Keane, VF Cruzat, R Carlessi… - Oxidative medicine …, 2015 - Wiley Online Library
The prevalence of diabetes mellitus (DM) is increasing worldwide, a consequence of the
alarming rise in obesity and metabolic syndrome (MetS). Oxidative stress and inflammation …

[HTML][HTML] The role of oxidative stress in the pathogenesis of type 2 diabetes: from molecular mechanism to clinical implication

YC Chang, LM Chuang - American journal of translational …, 2010 - ncbi.nlm.nih.gov
A surplus of food supply has evoked a worldwide increase in incidence of type 2 diabetes.
This trend will have a significant impact on the life span of people living in modern societies …

Oxidative stress, insulin signaling, and diabetes

JL Rains, SK Jain - Free radical biology and medicine, 2011 - Elsevier
Oxidative stress has been implicated as a contributor to both the onset and the progression
of diabetes and its associated complications. Some of the consequences of an oxidative …

[HTML][HTML] Oxidative stress in type 2 diabetes: impacts from pathogenesis to lifestyle modifications

A Caturano, M D'Angelo, A Mormone, V Russo… - Current Issues in …, 2023 - mdpi.com
Oxidative stress is a critical factor in the pathogenesis and progression of diabetes and its
associated complications. The imbalance between reactive oxygen species (ROS) …

Oxidative stress in diabetes

K Stadler - Diabetes: An Old Disease, a New Insight, 2013 - Springer
Oxidative stress and diabetes, both Type 1 and Type 2 as well as their related conditions
have been extensively studied. As diabetes, obesity and metabolic syndrome have reached …

[HTML][HTML] The etiology of oxidative stress in insulin resistance

S Hurrle, WH Hsu - Biomedical journal, 2017 - Elsevier
Insulin resistance is a prevalent syndrome in developed as well as developing countries. It is
the predisposing factor for type 2 diabetes mellitus, the most common end stage …

Proposed mechanisms for the induction of insulin resistance by oxidative stress

A Bloch-Damti, N Bashan - Antioxidants & redox signaling, 2005 - liebertpub.com
In diabetes (type 1 and type 2), increased flux of free fatty acids and glucose is associated
with increased mitochondrial reactive oxygen species (ROS) production and, as a …

[HTML][HTML] Mechanistic insight into oxidative stress-triggered signaling pathways and type 2 diabetes

A Singh, R Kukreti, L Saso, S Kukreti - Molecules, 2022 - mdpi.com
Oxidative stress (OS) is a metabolic dysfunction mediated by the imbalance between the
biochemical processes leading to elevated production of reactive oxygen species (ROS) …

Oxidative stress in the pathophysiology of type 2 diabetes and related complications: Current therapeutics strategies and future perspectives

JS Bhatti, A Sehrawat, J Mishra, IS Sidhu… - Free Radical Biology …, 2022 - Elsevier
Abstract Type 2 diabetes (T2DM) is a persistent metabolic disorder rising rapidly worldwide.
It is characterized by pancreatic insulin resistance and β-cell dysfunction. Hyperglycemia …