Chronic infections are an increasing problem due to the aging population and the increase
in antibiotic resistant organisms. Therefore, understanding the host-pathogen interactions …

Recurrent bacterial infections are a significant burden worldwide, and prior history of
infection is often a significant risk factor for developing new infections. For urinary tract …

Paradigms in the pathogenesis of urinary tract infections have shifted dramatically as a
result of recent scientific revelations. Beyond extracellular colonization of the bladder …

Urinary tract infections (UTIs) exert a significant health and economic cost globally.
Approximately one in four people with a previous history of UTI continue to develop …

Recent advances in preclinical modeling of urinary tract infections (UTIs) have enabled the
identification of key facets of the host response that influence pathogen clearance and tissue …

Urinary tract infections (UTI) are among the most common infections in humans.
Uropathogenic E scherichia coli (UPEC) can invade and replicate within bladder epithelial …

Previous urinary tract infections (UTIs) can predispose one to future infections; however, the
underlying mechanisms affecting recurrence are poorly understood. We previously found …

Uropathogenic Escherichia coli (UPEC), the most frequent cause of urinary tract infection
(UTI), is associated with an inflammatory response which includes the induction of …

Early transcriptional activation events that occur in bladder immediately following bacterial
urinary tract infection (UTI) are not well defined. In this study, we describe the whole bladder …

Bladder infections affect millions of people yearly, and recurrent symptomatic infections
(cystitis) are very common. The rapid increase in infections caused by multidrug-resistant …