[HTML][HTML] Chitosan-decorated and tripolyphosphate-crosslinked pH-sensitive niosomal nanogels for Controlled release of fluoropyrimidine 5-fluorouracil

MM Ahmed, MSM Ameen, M Abazari… - Biomedicine & …, 2023 - Elsevier
Highlights•5-fluorouracil, the common cancer treatment chemotherapy agent, has
significantly limited efficacy.•Chitosan-decorated and TPP-crosslinked niosomal nanogels …

The effect of niosome preparation methods in encapsulating 5-fluorouracil and real time cell assay against HCT-116 colon cancer cell line

OL Ugorji, ONC Umeh, CO Agubata, D Adah, NC Obitte… - Heliyon, 2022 - cell.com
The formulation of niosomes is influenced by a number of variables, and these variables
may eventually affect the formulation's outcome. One of the elements that can influence the …

Polymeric chitosan based nanogels as a potential platform for dual targeted drug delivery in cancer therapy

TV Tran, THD Phuong, NQ Tran… - International …, 2018 - inderscienceonline.com
Dual-drug delivery system (DDDS) is reported as an outstanding candidate for the treatment
of cancer. In this study, self-assembled nanogels were fabricated using poly (ethylene …

Folic acid-functionalized niosomal nanoparticles for selective dual-drug delivery into breast cancer cells: An in-vitro investigation

I Akbarzadeh, MT Yaraki, S Ahmadi, M Chiani… - Advanced Powder …, 2020 - Elsevier
In this study, a folic acid-functionalized niosome was formulated and loaded with letrozole
and curcumin as a promising drug carrier system for chemotherapy of the breast cancer …

Methacrylic-based nanogels for the pH-sensitive delivery of 5-fluorouracil in the colon

N Ashwanikumar, NA Kumar, SA Nair… - International journal of …, 2012 - Taylor & Francis
Methacrylic-based copolymers in drug-delivery systems demonstrate a pH-sensitive drug-
releasing behavior in the colon. In this study, copolymers of methacrylic acid and 2-ethyl …

Folic acid-functionalized PEGylated niosomes co-encapsulated cisplatin and doxoribicin exhibit enhanced anticancer efficacy

M Safari Sharafshadeh, F Tafvizi, P Khodarahmi… - Cancer …, 2024 - Springer
The medical field is faced with the difficult task of developing a new approach to curing
cancer, which is prevalent in organs such as the breast and ovaries and has a high mortality …

pH-sensitive chitosan-folate nanogels crosslinked with biocompatible dicarboxylic acids

MA Pujana, L Pérez-Álvarez, LCC Iturbe… - European polymer …, 2014 - Elsevier
Chitosan nanogels functionalized with folic acid and crosslinked with PEG diacid or tartaric
acid have been prepared by inverse microemulsion method for targeted delivery into cancer …

Assessment of penetration potential of pH responsive double walled biodegradable nanogels coated with eucalyptus oil for the controlled delivery of 5-fluorouracil: In …

P Sahu, SK Kashaw, S Jain, S Sau, AK Iyer - Journal of Controlled Release, 2017 - Elsevier
Penetration enhancers coated biodegradable polymeric nanogels loaded with cytotoxic
drugs applied via the topical route, can be a promising strategy for improving the …

Preparation and characterization of 5-fluorouracil pH-sensitive niosome and its tumor-targeted evaluation: in vitro and in vivo

M Wang, Y Yuan, Y Gao, HM Ma, HT Xu… - Drug Development …, 2012 - Taylor & Francis
The purpose of this study was to investigate preparation, characterization and tumor-
targeted effect of pH-sensitive niosomes, composed of a nonionic surfactant mixed with …

[HTML][HTML] pH-sensitive, polymer modified, plasma stable niosomes: promising carriers for anti-cancer drugs

D Tila, SN Yazdani-Arazi, S Ghanbarzadeh… - EXCLI …, 2015 - ncbi.nlm.nih.gov
The aim of this study was the design and evaluation of a novel plasma stable, pH-sensitive
niosomal formulation of Mitoxantrone by a modified ethanol injection method. Cholesterol …