The chemistry of organic contrast agents in the NIR‐II window

J Mu, M Xiao, Y Shi, X Geng, H Li… - Angewandte Chemie …, 2022 - Wiley Online Library
Optical imaging, especially fluorescence and photoacoustic imaging, is a non‐invasive
imaging approach with high spatial and temporal resolution and high sensitivity, compared …

Molecular fluorescence and photoacoustic imaging in the second near‐infrared optical window using organic contrast agents

Y Jiang, K Pu - Advanced Biosystems, 2018 - Wiley Online Library
Noninvasive near‐infrared (NIR) light ranging from 650 to 1000 nm (NIR‐I) is widely
employed in fundamental research and clinical applications; however, a recently discovered …

A Class of Activatable NIR‐II Photoacoustic Dyes for High‐Contrast Bioimaging

J Li, J Wang, L Xu, H Chi, X Liang, J Yoon… - Angewandte …, 2024 - Wiley Online Library
Photoacoustic (PA) imaging is emerging as one of the important non‐invasive imaging
techniques in biomedical research. Small molecule‐second near‐infrared window (NIR‐II) …

NIR-II functional materials for photoacoustic theranostics

Z Li, C Zhang, X Zhang, J Sui, L Jin, L Lin… - Bioconjugate …, 2022 - ACS Publications
Photoacoustic imaging (PAI) has attracted great attention in the diagnosis and treatment of
diseases due to its noninvasive properties. Especially in the second near-infrared (NIR-II) …

Development of second near-infrared photoacoustic imaging agents

J Zhang, L Ning, Z Zeng, K Pu - Trends in Chemistry, 2021 - cell.com
Photoacoustic imaging (PAI) has attracted increasing attention both in basic research and
clinical applications. PAI in the second near-infrared (NIR-II) window shows deeper …

Organic semiconducting agents for deep‐tissue molecular imaging: second near‐infrared fluorescence, self‐luminescence, and photoacoustics

Q Miao, K Pu - Advanced materials, 2018 - Wiley Online Library
Optical imaging has played a pivotal role in biology and medicine, but it faces challenges of
relatively low tissue penetration and poor signal‐to‐background ratio due to light scattering …

Blending Low‐Frequency Vibrations and Push–Pull Effects Affords Superior Photoacoustic Imaging Agents

L Yu, SA Abbas Abedi, J Lee, Y Xu… - Angewandte Chemie …, 2023 - Wiley Online Library
Photoacoustic imaging (PAI), a state‐of‐the‐art noninvasive in vivo imaging technique, has
been widely used in clinical disease diagnosis. However, the design of high‐performance …

Molecular photoacoustic contrast agents: design principles & applications

RE Borg, J Rochford - Photochemistry and photobiology, 2018 - Wiley Online Library
Photoacoustic imaging (PAI) is a rapidly growing field which offers high spatial resolution
and high contrast for deep‐tissue imaging in vivo. PAI is nonionizing and noninvasive and …

Side‐Chain‐Tuned Molecular Packing Allows Concurrently Boosted Photoacoustic Imaging and NIR‐II Fluorescence

Y Zhu, H Lai, H Guo, D Peng, L Han… - Angewandte Chemie …, 2022 - Wiley Online Library
It is generally considered that photoacoustic imaging (PAI) and fluorescence imaging (FLI)
cannot be enhanced concurrently, as they are dependent on competitive photophysical …

Synthesis, characterization, and biomedical applications of a targeted dual-modal near-infrared-II fluorescence and photoacoustic imaging nanoprobe

K Cheng, H Chen, CH Jenkins, G Zhang, W Zhao… - ACS …, 2017 - ACS Publications
Our development of multifunctional dual-modal imaging probes aims to integrate the
benefits from both second near-infrared (NIR-II) fluorescence (1000–1700 nm) and …