[HTML][HTML] Targeting ferroptosis by poly(acrylic) acid coated Mn3O4 nanoparticles alleviates acute liver injury

X Shan, J Li, J Liu, B Feng, T Zhang, Q Liu… - Nature …, 2023 - nature.com
Ferroptosis, a newly characterized form of regulated cell death, is induced by excessive
accumulation of lipid peroxidation catalyzed by intracellular bioactive iron. Increasing …

A nonferrous ferroptosis-like strategy for antioxidant inhibition–synergized nanocatalytic tumor therapeutics

C Wu, Z Liu, Z Chen, D Xu, L Chen, H Lin, J Shi - Science advances, 2021 - science.org
Ferroptosis, an emerging type of cell death found in the past decades, features specifically
lipid peroxidation during the cell death process commonly by iron accumulation …

Targeting ferroptosis by polydopamine nanoparticles protects heart against ischemia/reperfusion injury

Y Zhang, X Ren, Y Wang, D Chen, L Jiang… - … applied materials & …, 2021 - ACS Publications
Ferroptosis is a new form of regulated cell death depending on elevated iron (Fe2+) and
lipid peroxidation levels. Myocardial ischemia/reperfusion (I/R) injury has been shown to be …

Disruption of dual homeostasis by a metal-organic framework nanoreactor for ferroptosis-based immunotherapy of tumor

K Zhang, Z Ma, S Li, Y Wu, J Zhang, W Zhang, Y Zhao… - Biomaterials, 2022 - Elsevier
Ferroptosis, a newfound non-apoptotic cell death pathway that is iron-and reactive oxygen
species (ROS)-dependent, has shown a promise for tumor treatment. However, engineering …

Spatially Asymmetric Nanoparticles for Boosting Ferroptosis in Tumor Therapy

M Hou, M Liu, H Yu, Y Kou, J Jia, Q Zhou, F Zhang… - Nano Letters, 2024 - ACS Publications
Despite its effectiveness in eliminating cancer cells, ferroptosis is hindered by the high
natural antioxidant glutathione (GSH) levels in the tumor microenvironment. Herein, we …

Overcoming Hypoxia‐Induced Ferroptosis Resistance via a 19F/1H‐MRI Traceable Core‐Shell Nanostructure

Z Dong, P Liang, G Guan, B Yin, Y Wang… - Angewandte Chemie …, 2022 - Wiley Online Library
Lipid peroxides accumulation induced ferroptosis is an effective cell death pathway for
cancer therapy. However, the hypoxic condition of tumor microenvironment significantly …

[HTML][HTML] The emerging role of ferroptosis in liver diseases

S Chen, J Zhu, X Zang, Y Zhai - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
Ferroptosis is a newly discovered type of cell death mediated by iron-dependent lipid
peroxide. The disturbance of iron metabolism, imbalance of the amino acid antioxidant …

Enhanced ferroptosis therapy with a “nano-destructor” by disrupting intracellular redox and iron homeostasis

T Song, G Yang, H Zhang, M Li, W Zhou, C Zheng… - Nano Today, 2023 - Elsevier
Ferroptosis is an iron-dependent form of cell death that is also a promising tumor therapeutic
modality, however, maintaining redox and iron homeostasis in tumor cells limits the …

[HTML][HTML] Induction of ferroptosis using functionalized iron-based nanoparticles for anti-cancer therapy

C Bae, H Kim, YM Kook, C Lee, C Kim, C Yang… - Materials Today Bio, 2022 - Elsevier
Ferroptosis, a cell death pathway that is induced in response to iron, has recently attracted
remarkable attention given its emerging therapeutic potential in cancer cells. The need for a …

Fenton reaction-independent ferroptosis therapy via glutathione and iron redox couple sequentially triggered lipid peroxide generator

YJ He, XY Liu, L Xing, X Wan, X Chang, HL Jiang - Biomaterials, 2020 - Elsevier
Ferroptosis, a newfound non-apoptotic cell death pathway, results from the accumulation of
iron-dependent lipid peroxide (LPO). Recently, emerging iron-based nanomaterials have …