Metals and mechanisms of carcinogenesis
Metal exposure is pervasive and not limited to sporadic poisoning events or toxic waste
sites. Hundreds of millions of people around the globe are affected by chronic metal …
sites. Hundreds of millions of people around the globe are affected by chronic metal …
Metals and molecular carcinogenesis
Y Zhu, M Costa - Carcinogenesis, 2020 - academic.oup.com
Many metals are essential for living organisms, but at higher doses they may be toxic and
carcinogenic. Metal exposure occurs mainly in occupational settings and environmental …
carcinogenic. Metal exposure occurs mainly in occupational settings and environmental …
Carcinogenic metal compounds: recent insight into molecular and cellular mechanisms
D Beyersmann, A Hartwig - Archives of toxicology, 2008 - Springer
Mechanisms of carcinogenicity are discussed for metals and their compounds, classified as
carcinogenic to humans or considered to be carcinogenic to humans: arsenic, antimony …
carcinogenic to humans or considered to be carcinogenic to humans: arsenic, antimony …
Epigenetic regulation in chromium-, nickel-and cadmium-induced carcinogenesis
L Zhao, R Islam, Y Wang, X Zhang, LZ Liu - Cancers, 2022 - mdpi.com
Simple Summary Environmental and occupational exposure to heavy metals are risk factors
for cancers. However, the molecular mechanisms of how heavy metals induce …
for cancers. However, the molecular mechanisms of how heavy metals induce …
Toxicological principles of metal carcinogenesis with special emphasis on cadmium
MP Waalkes, TP Coogan, RA Barter - Critical reviews in toxicology, 1992 - Taylor & Francis
Metals are an important and emerging class of carcinogens. At least three metals,
specifically nickel, chromium, and arsenic, are confirmed human carcinogens, and several …
specifically nickel, chromium, and arsenic, are confirmed human carcinogens, and several …
Metal-induced carcinogenesis, oxidative stress and hypoxia signalling
A Galanis, A Karapetsas, R Sandaltzopoulos - Mutation research/Genetic …, 2009 - Elsevier
Heavy metal-induced carcinogenesis is well documented by epidemiological studies.
Several diverse mechanisms of cancer induction may be involved, depending on the form of …
Several diverse mechanisms of cancer induction may be involved, depending on the form of …
Metal carcinogenesis: mechanistic implications
ET Snow - Pharmacology & therapeutics, 1992 - Elsevier
Cancer epidemiology has identified several metal compounds as human carcinogens.
Recent evidence suggests that carcinogenic metals induce genotoxicity in a multiplicity of …
Recent evidence suggests that carcinogenic metals induce genotoxicity in a multiplicity of …
Signaling by carcinogenic metals and metal-induced reactive oxygen species
GK Harris, X Shi - … Research/Fundamental and Molecular Mechanisms of …, 2003 - Elsevier
Epidemiological data indicate that exposure to metal and metalloid species, including
arsenic (III), chromium (VI), and nickel (II), increases the risk of cancer, particularly of the …
arsenic (III), chromium (VI), and nickel (II), increases the risk of cancer, particularly of the …
Mechanisms in cadmium-induced carcinogenicity: recent insights
A Hartwig - Biometals, 2010 - Springer
Cadmium is an environmental pollutant, with relevant exposures at workplaces and in the
general population. The carcinogenicity has been long established, most evident for tumors …
general population. The carcinogenicity has been long established, most evident for tumors …
Metal ions in human cancer development
EJ Tokar, L Benbrahim-Tallaa - 2010 - books.rsc.org
Metals have been in the environment during the entire evolution of man and the use of
metals is key to human civilization. None-the-less, several very toxic species are included in …
metals is key to human civilization. None-the-less, several very toxic species are included in …