[HTML][HTML] HIV-specific antibodies capable of ADCC are common in breastmilk and are associated with reduced risk of transmission in women with high viral loads
J Mabuka, R Nduati, K Odem-Davis, D Peterson… - PLoS …, 2012 - journals.plos.org
There are limited data describing the functional characteristics of HIV-1 specific antibodies in
breast milk (BM) and their role in breastfeeding transmission. The ability of BM antibodies to …
breast milk (BM) and their role in breastfeeding transmission. The ability of BM antibodies to …
HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies
Despite months of mucosal virus exposure, the majority of breastfed infants born to HIV-
infected mothers do not become infected, raising the possibility that immune factors in milk …
infected mothers do not become infected, raising the possibility that immune factors in milk …
The breadth and potency of passively acquired human immunodeficiency virus type 1-specific neutralizing antibodies do not correlate with the risk of infant infection
Although a major goal of human immunodeficiency virus type 1 (HIV-1) vaccine efforts is to
elicit broad and potent neutralizing antibodies (NAbs), there are no data that directly …
elicit broad and potent neutralizing antibodies (NAbs), there are no data that directly …
Association of HIV-1 envelope-specific breast milk IgA responses with reduced risk of postnatal mother-to-child transmission of HIV-1
J Pollara, E McGuire, GG Fouda, W Rountree… - Journal of …, 2015 - Am Soc Microbiol
Infants born to HIV-1-infected mothers in resource-limited areas where replacement feeding
is unsafe and impractical are repeatedly exposed to HIV-1 throughout breastfeeding …
is unsafe and impractical are repeatedly exposed to HIV-1 throughout breastfeeding …
Women with cervicovaginal antibody-dependent cell-mediated cytotoxicity have lower genital HIV-1 RNA loads
P Nag, J Kim, V Sapiega, AL Landay… - The Journal of …, 2004 - academic.oup.com
Antibodies that mediate human immunodeficiency virus (HIV)-specific antibody-dependent
cell-mediated cytotoxicity (ADCC) are present in the cervical fluid of many HIV-positive …
cell-mediated cytotoxicity (ADCC) are present in the cervical fluid of many HIV-positive …
Transmission of cell-free and cell-associated HIV-1 through breast-feeding
IN Koulinska, E Villamor, B Chaplin… - JAIDS Journal of …, 2006 - journals.lww.com
Background: Transmission through breast-feeding is an important cause of infant HIV-1
infections in developing countries; however, its mechanism remains largely unknown. We …
infections in developing countries; however, its mechanism remains largely unknown. We …
Association of levels of HIV-1—infected breast milk cells and risk of mother-to-child transmission
CM Rousseau, RW Nduati… - The Journal of …, 2004 - academic.oup.com
Understanding how the level of human immunodeficiency virus type 1 (HIV-1)-infected
breast milk cells (BMCs) affects HIV transmission via breast-feeding can shed light on the …
breast milk cells (BMCs) affects HIV transmission via breast-feeding can shed light on the …
[HTML][HTML] Maternal HIV-1 envelope–specific antibody responses and reduced risk of perinatal transmission
Despite the wide availability of antiretroviral drugs, more than 250,000 infants are vertically
infected with HIV-1 annually, emphasizing the need for additional interventions to eliminate …
infected with HIV-1 annually, emphasizing the need for additional interventions to eliminate …
Human Immunodeficiency Virus-Specific CD8+ T Cells in Human Breast Milk
S Sabbaj, BH Edwards, MK Ghosh, K Semrau… - Journal of …, 2002 - Am Soc Microbiol
Breast-feeding infants of human immunodeficiency virus (HIV)-infected women ingest large
amounts of HIV, but most escape infection. While the factors affecting transmission risk are …
amounts of HIV, but most escape infection. While the factors affecting transmission risk are …
Cell-free virus in breast milk of HIV-1-seropositive women
K Pillay, A Coutsoudis, D York, L Kuhn… - JAIDS Journal of …, 2000 - journals.lww.com
To examine the prevalence, quantification, and factors that influence HIV in the cell-free
compartment of breast milk, we performed reverse transcription polymerase chain reaction …
compartment of breast milk, we performed reverse transcription polymerase chain reaction …