[HTML][HTML] HIV-specific antibodies capable of ADCC are common in breastmilk and are associated with reduced risk of transmission in women with high viral loads

J Mabuka, R Nduati, K Odem-Davis, D Peterson… - PLoS …, 2012 - journals.plos.org
There are limited data describing the functional characteristics of HIV-1 specific antibodies in
breast milk (BM) and their role in breastfeeding transmission. The ability of BM antibodies to …

HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies

GG Fouda, NL Yates, J Pollara, X Shen… - Journal of …, 2011 - Am Soc Microbiol
Despite months of mucosal virus exposure, the majority of breastfed infants born to HIV-
infected mothers do not become infected, raising the possibility that immune factors in milk …

The breadth and potency of passively acquired human immunodeficiency virus type 1-specific neutralizing antibodies do not correlate with the risk of infant infection

JB Lynch, R Nduati, CA Blish, BA Richardson… - Journal of …, 2011 - Am Soc Microbiol
Although a major goal of human immunodeficiency virus type 1 (HIV-1) vaccine efforts is to
elicit broad and potent neutralizing antibodies (NAbs), there are no data that directly …

Association of HIV-1 envelope-specific breast milk IgA responses with reduced risk of postnatal mother-to-child transmission of HIV-1

J Pollara, E McGuire, GG Fouda, W Rountree… - Journal of …, 2015 - Am Soc Microbiol
Infants born to HIV-1-infected mothers in resource-limited areas where replacement feeding
is unsafe and impractical are repeatedly exposed to HIV-1 throughout breastfeeding …

Women with cervicovaginal antibody-dependent cell-mediated cytotoxicity have lower genital HIV-1 RNA loads

P Nag, J Kim, V Sapiega, AL Landay… - The Journal of …, 2004 - academic.oup.com
Antibodies that mediate human immunodeficiency virus (HIV)-specific antibody-dependent
cell-mediated cytotoxicity (ADCC) are present in the cervical fluid of many HIV-positive …

Transmission of cell-free and cell-associated HIV-1 through breast-feeding

IN Koulinska, E Villamor, B Chaplin… - JAIDS Journal of …, 2006 - journals.lww.com
Background: Transmission through breast-feeding is an important cause of infant HIV-1
infections in developing countries; however, its mechanism remains largely unknown. We …

Association of levels of HIV-1—infected breast milk cells and risk of mother-to-child transmission

CM Rousseau, RW Nduati… - The Journal of …, 2004 - academic.oup.com
Understanding how the level of human immunodeficiency virus type 1 (HIV-1)-infected
breast milk cells (BMCs) affects HIV transmission via breast-feeding can shed light on the …

[HTML][HTML] Maternal HIV-1 envelope–specific antibody responses and reduced risk of perinatal transmission

SR Permar, Y Fong, N Vandergrift… - The Journal of …, 2015 - Am Soc Clin Investig
Despite the wide availability of antiretroviral drugs, more than 250,000 infants are vertically
infected with HIV-1 annually, emphasizing the need for additional interventions to eliminate …

Human Immunodeficiency Virus-Specific CD8+ T Cells in Human Breast Milk

S Sabbaj, BH Edwards, MK Ghosh, K Semrau… - Journal of …, 2002 - Am Soc Microbiol
Breast-feeding infants of human immunodeficiency virus (HIV)-infected women ingest large
amounts of HIV, but most escape infection. While the factors affecting transmission risk are …

Cell-free virus in breast milk of HIV-1-seropositive women

K Pillay, A Coutsoudis, D York, L Kuhn… - JAIDS Journal of …, 2000 - journals.lww.com
To examine the prevalence, quantification, and factors that influence HIV in the cell-free
compartment of breast milk, we performed reverse transcription polymerase chain reaction …