We show how dynamic nuclear polarization (DNP) enhanced solid-state NMR spectroscopy
can be used to characterize polymorphs and solvates of organic solids. We applied DNP to …

When determining crystal structures of organic molecular materials from high-resolution
powder diffraction data, the key step is the generation of reliable trial structures for final …

Dynamic nuclear polarization (DNP) enhanced solid-state NMR spectroscopy at 9.4 T is
demonstrated for the detailed atomic-level characterization of commercial pharmaceutical …

Multicomponent solids such as cocrystals have emerged as a way to control and engineer
the stability, solubility, and manufacturability of solid active pharmaceutical ingredients …

Magic‐angle spinning NMR is now making a significant contribution to our understanding of
the structure of polymorphs and solvates of pharmaceutical significance. This personal …

Solid‐state NMR spectroscopy has become a valuable tool for the characterization of both
pure and formulated active pharmaceutical ingredients (APIs). However, NMR generally …

In this work, we show how to obtain efficient dynamic nuclear polarization (DNP) enhanced
35Cl solid-state NMR (SSNMR) spectra at 9.4 T and demonstrate how they can be used to …

A principal advantage of magic angle spinning (MAS) NMR spectroscopy lies in its ability to
determine molecular structure in a noninvasive and quantitative manner. Accordingly, MAS …

Efficient dynamic nuclear polarization (DNP) in solids, which enables very high sensitivity
NMR experiments, is currently limited to temperatures of around 100 K and below. Here we …

The technique of solid-state NMR, as applied to pharmaceutical analysis, has evolved from
a sparingly used technique into an integrated, information-rich technique that uses a variety …