[HTML][HTML] Pain and the triple network model
Acute pain is a physiological response that causes an unpleasant sensory and emotional
experience in the presence of actual or potential tissue injury. Anatomically and …
experience in the presence of actual or potential tissue injury. Anatomically and …
Brain systems at the intersection of chronic pain and self-regulation
Chronic pain is a multidimensional experience with cognitive, affective, and somatosensory
components that can be modified by expectations and learning. Individual differences in …
components that can be modified by expectations and learning. Individual differences in …
[HTML][HTML] Gray matter alterations in chronic pain: a network-oriented meta-analytic approach
Several studies have attempted to characterize morphological brain changes due to chronic
pain. Although it has repeatedly been suggested that longstanding pain induces gray matter …
pain. Although it has repeatedly been suggested that longstanding pain induces gray matter …
[HTML][HTML] The anatomy of pain and suffering in the brain and its clinical implications
Pain is an unpleasant sensory and emotional experience associated with actual or potential
tissue damage. Chronic pain, with a prevalence of 20–30% is the major cause of human …
tissue damage. Chronic pain, with a prevalence of 20–30% is the major cause of human …
Exploring the brain in pain: activations, deactivations and their relation
The majority of neuroimaging studies on pain focuses on the study of BOLD activations, and
more rarely on deactivations. In this study, in a relatively large cohort of subjects (N= 61), we …
more rarely on deactivations. In this study, in a relatively large cohort of subjects (N= 61), we …
Altered resting state attentional networks in diabetic neuropathic pain
Background Chronic pain can be considered as a highly salient stimulus that continuously
taxes the attentional and salience processing networks, thus interfering with cognitive …
taxes the attentional and salience processing networks, thus interfering with cognitive …
Perturbed connectivity of the amygdala and its subregions with the central executive and default mode networks in chronic pain
Maladaptive responses to pain-related distress, such as pain catastrophizing, amplify the
impairments associated with chronic pain. Many of these aspects of chronic pain are similar …
impairments associated with chronic pain. Many of these aspects of chronic pain are similar …
Psychological processing in chronic pain: a neural systems approach
LE Simons, I Elman, D Borsook - Neuroscience & Biobehavioral Reviews, 2014 - Elsevier
Our understanding of chronic pain involves complex brain circuits that include sensory,
emotional, cognitive and interoceptive processing. The feed-forward interactions between …
emotional, cognitive and interoceptive processing. The feed-forward interactions between …
[HTML][HTML] Threat response system: parallel brain processes in pain vis-à-vis fear and anxiety
I Elman, D Borsook - Frontiers in psychiatry, 2018 - frontiersin.org
Pain is essential for avoidance of tissue damage and for promotion of healing.
Notwithstanding the survival value, pain brings about emotional suffering reflected in fear …
Notwithstanding the survival value, pain brings about emotional suffering reflected in fear …
[HTML][HTML] Pain-free resting-state functional brain connectivity predicts individual pain sensitivity
T Spisak, B Kincses, F Schlitt, M Zunhammer… - Nature …, 2020 - nature.com
Individual differences in pain perception are of interest in basic and clinical research as
altered pain sensitivity is both a characteristic and a risk factor for many pain conditions. It is …
altered pain sensitivity is both a characteristic and a risk factor for many pain conditions. It is …