5-HT7 Receptor Contributes to Proliferation, Migration and Invasion in NSCLC Cells
X Du, T Wang, Z Wang, X Wu, Y Gu… - OncoTargets and …, 2020 - Taylor & Francis
Introduction Because only a small portion of NSCLC (non-small-cell lung cancer) patients
benefit from molecular targeted therapy or immunotherapy and do not develop therapeutic …
benefit from molecular targeted therapy or immunotherapy and do not develop therapeutic …
STUDY OF 5HT3 AND 5HT4 RECEPTORSEXPRESSION IN HT29 CELL LINE AND HUMAN COLON ADENOCARCINOMA TISSUES
Background: SEROTONIN (5HT) has been shown to be a mitogenic factor in several
carcinomas. Its mitogenic effect is elicited through a wide range of 5HT receptor subtypes. In …
carcinomas. Its mitogenic effect is elicited through a wide range of 5HT receptor subtypes. In …
5-Hydroxytryptamine activates a 5-HT/c-Myc/SLC6A4 signaling loop in non–small cell lung cancer
Y Tu, S Yao, Q Chen, W Li, Y Song, P Zhang - Biochimica et Biophysica …, 2022 - Elsevier
Purpose Psychological stress is a crucial driver of tumorigenesis and cancer metastasis. The
impact of the stress-associated neurotransmitter 5-hydroxytryptamine (5-HT) on tumor …
impact of the stress-associated neurotransmitter 5-hydroxytryptamine (5-HT) on tumor …
The role of 5-HT1A receptor in cancer as a new opportunity in medicinal chemistry
A Corvino, F Fiorino, B Severino… - Current Medicinal …, 2018 - ingentaconnect.com
The 5-HT1A receptor is a pharmacologically well characterized serotonin receptor subtype
and it has long been investigated because of its involvement in several physiopathological …
and it has long been investigated because of its involvement in several physiopathological …
5-HT7 receptors as a new target for prostate cancer physiopathology and treatment: an experimental study on PC-3 cells and FFPE tissues
Prostate cancer (PCa) is one of the most common types of cancer seen among men
worldwide. Previous studies have demonstrated that serotonin regulates cell proliferation …
worldwide. Previous studies have demonstrated that serotonin regulates cell proliferation …
Anti-mitogenic and apoptotic effects of 5-HT1B receptor antagonist on HT29 colorectal cancer cell line
Purpose There is lack of evidence about impact of 5-HT receptors on colorectal cancers. The
current study was designed to investigate the role of serotonin and its receptors in colorectal …
current study was designed to investigate the role of serotonin and its receptors in colorectal …
[HTML][HTML] 5-hydroxytryptamine receptor (5-HT1DR) promotes colorectal cancer metastasis by regulating Axin1/β-catenin/MMP-7 signaling pathway
H Sui, H Xu, Q Ji, X Liu, L Zhou, H Song, X Zhou, Y Xu… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Abstract Overexpression of 5-hydroxytryptamine (5-HT) in human cancer contributes to
tumor metastasis, but the role of 5-HT receptor family in cancer has not been thoroughly …
tumor metastasis, but the role of 5-HT receptor family in cancer has not been thoroughly …
Downregulation of 5‑hydroxytryptamine receptor 3A expression exerts an anticancer activity against cell growth in colorectal carcinoma cells in vitro
J Tang, Z Wang, J Liu, C Zhou… - Oncology letters, 2018 - spandidos-publications.com
hydroxytryptamine receptor 3A (HTR3A) is an important member of the 5‑HT family, which
has been suggested to contribute to human tumor development. However, the functions of …
has been suggested to contribute to human tumor development. However, the functions of …
HTR3A is correlated with unfavorable histology and promotes proliferation through ERK phosphorylation in lung adenocarcinoma
M Tone, S Tahara, S Nojima, D Motooka… - Cancer …, 2020 - Wiley Online Library
Lung cancer is the leading cause of cancer death around the world. Adenocarcinoma is the
most common histological type and has various histologic subtypes: lepidic, acinar …
most common histological type and has various histologic subtypes: lepidic, acinar …
[HTML][HTML] HTR7 promotes laryngeal cancer growth through PI3K/AKT pathway activation
X Sheng, W Liu, Z Lu, M Xu, R Li, R Zhong… - Annals of …, 2021 - ncbi.nlm.nih.gov
Background Laryngeal cancer is a common malignancy of the head and neck, it's important
to find novel targets for its therapy. The 5-hydroxytryptamine receptor 7 (HTR7) belongs to …
to find novel targets for its therapy. The 5-hydroxytryptamine receptor 7 (HTR7) belongs to …