The activation of ferroptosis is a new effective way to treat drug-resistant solid tumors.
Ferroptosis is an iron-mediated form of cell death caused by the accumulation of lipid …

Background Cancer is one of the major threats to human health and current cancer
therapies have been unsuccessful in eradicating it. Ferroptosis is characterized by iron …

Ferroptosis, characterized by excessive iron accumulation and lipid peroxidation, is a novel
form of iron-dependent cell death, which is morphologically, genetically, and biochemically …

Ferroptosis is a type of oxidative stress-dependent regulated necrosis characterized by
excessive lipid peroxide accumulation. This novel cell death modality has been implicated in …

The development of chemotherapy drugs has promoted anticancer treatment, but the effect
on tumours is not clear because of treatment resistance; thus, it is necessary to further …

Iron-dependent ferroptosis is a new form of cell death in recent years, which is driven by lipid
peroxidation. The lethal lipid accumulation caused by glutathione depletion or inactivation of …

Ferroptosis is a process driven by accumulated iron-dependent lipid ROS that leads to cell
death, which is a distinct regulated cell death comparing to other cell death. The lethal …

Ferroptosis is an atypical form of regulated cell death, which is different from apoptosis,
necrosis, pyroptosis, and autophagy. Ferroptosis is characterized by iron‐dependent …

Ferroptosis is a recently described programmed cell death mechanism that is characterized
by the buildup of iron (Fe)-dependent lipid peroxides in cells and is morphologically …

The system XC−/glutathione/glutathione peroxidase 4 (Gpx4) axis pivotally controls
ferroptosis, a recently described form of regulated non-apoptotic cell death. Compelling …