Analysis of the critical domain in the V3 loop of human immunodeficiency virus type 1 gp120 involved in CCR5 utilization
CS Hung, N Vander Heyden, L Ratner - Journal of virology, 1999 - Am Soc Microbiol
Human immunodeficiency virus type 1 (HIV-1) infection of CD4+ lymphocytes and
macrophages involves interaction of the surface subunit of the envelope protein (gp120) …
macrophages involves interaction of the surface subunit of the envelope protein (gp120) …
Effect of amino acid substitution of the V3 and bridging sheet residues in human immunodeficiency virus type 1 subtype C gp120 on CCR5 utilization
P Suphaphiphat, A Thitithanyanont… - Journal of …, 2003 - Am Soc Microbiol
The V3 loop and the bridging sheet domain of human immunodeficiency virus type 1 (HIV-1)
subtype B envelope glycoprotein gp120 have been implicated in CCR5 coreceptor …
subtype B envelope glycoprotein gp120 have been implicated in CCR5 coreceptor …
The crown and stem of the V3 loop play distinct roles in human immunodeficiency virus type 1 envelope glycoprotein interactions with the CCR5 coreceptor
EG Cormier, T Dragic - Journal of virology, 2002 - Am Soc Microbiol
Human immunodeficiency virus type 1 envelope glycoprotein gp120 interacts with CD4 and
the CCR5 coreceptor in order to mediate viral entry. A CD4-induced surface on gp120 …
the CCR5 coreceptor in order to mediate viral entry. A CD4-induced surface on gp120 …
[HTML][HTML] An altered and more efficient mechanism of CCR5 engagement contributes to macrophage tropism of CCR5-using HIV-1 envelopes
J Sterjovski, M Roche, MJ Churchill, A Ellett… - Virology, 2010 - Elsevier
While CCR5 is the principal coreceptor used by macrophage (M)-tropic HIV-1, not all
primary CCR5-using (R5) viruses enter macrophages efficiently. Here, we used functionally …
primary CCR5-using (R5) viruses enter macrophages efficiently. Here, we used functionally …
Identification of conserved and variable structures in the human immunodeficiency virus gp120 glycoprotein of importance for CXCR4 binding
S Basmaciogullari, GJ Babcock, D Van Ryk… - Journal of …, 2002 - Am Soc Microbiol
ABSTRACT CD4 and the chemokine receptors, CXCR4 and CCR5, serve as receptors for
human immunodeficiency virus type 1 (HIV-1). Binding of the HIV-1 gp120 envelope …
human immunodeficiency virus type 1 (HIV-1). Binding of the HIV-1 gp120 envelope …
CCR5 coreceptor utilization involves a highly conserved arginine residue of HIV type 1 gp120
WK Wang, T Dudek, YJ Zhao… - Proceedings of the …, 1998 - National Acad Sciences
The seven-transmembrane CCR5 was recently found to double as a coreceptor for a
genetically diverse family of human and nonhuman primate lentiviruses. Paradoxically, the …
genetically diverse family of human and nonhuman primate lentiviruses. Paradoxically, the …
Cooperation of the V1/V2 and V3 domains of human immunodeficiency virus type 1 gp120 for interaction with the CXCR4 receptor
B Labrosse, C Treboute, A Brelot, M Alizon - Journal of virology, 2001 - Am Soc Microbiol
Human immunodeficiency virus type 1 (HIV-1) entry is triggered by the interaction of the
gp120 envelope glycoprotein with a cellular chemokine receptor, either CCR5 or CXCR4 …
gp120 envelope glycoprotein with a cellular chemokine receptor, either CCR5 or CXCR4 …
Restricted variable residues in the C-terminal segment of HIV-1 V3 loop regulate the molecular anatomy of CCR5 utilization
Q Hu, KB Napier, JO Trent, Z Wang, S Taylor… - Journal of molecular …, 2005 - Elsevier
The V3 loop of the HIV-1 envelope glycoprotein (Env) is the major determinant for
coreceptor utilization, but the structural basis for this specificity remains to be defined. By …
coreceptor utilization, but the structural basis for this specificity remains to be defined. By …
[HTML][HTML] Mutations in the V3 stem versus the V3 crown and C4 region have different effects on the binding and fusion steps of human immunodeficiency virus type 1 …
P Suphaphiphat, M Essex, TH Lee - Virology, 2007 - Elsevier
The current model for HIV-1 envelope–coreceptor interaction depicts the V3 stem and
bridging sheet binding to the CCR5 N-terminus while the V3 crown interacts with the second …
bridging sheet binding to the CCR5 N-terminus while the V3 crown interacts with the second …
Mapping the determinants of the CCR5 amino-terminal sulfopeptide interaction with soluble human immunodeficiency virus type 1 gp120-CD4 complexes
EG Cormier, DNH Tran, L Yukhayeva… - Journal of …, 2001 - Am Soc Microbiol
ABSTRACT CD4 and CCR5 mediate fusion and entry of R5 human immunodeficiency virus
type 1 (HIV-1) strains. Sulfotyrosine and other negatively charged residues in the CCR5 …
type 1 (HIV-1) strains. Sulfotyrosine and other negatively charged residues in the CCR5 …