Anion gap as a prognostic tool for risk stratification in critically ill patients–a systematic review and meta-analysis

SA Glasmacher, W Stones - BMC anesthesiology, 2015 - Springer
Background Lactate concentration is a robust predictor of mortality but in many low resource
settings facilities for its analysis are not available. Anion gap (AG), calculated from clinical …

Unmeasured anions and mortality in critically ill patients in 2016

Y Kotake - Journal of intensive care, 2016 - Springer
The presence of acid-base disturbances, especially metabolic acidosis may negatively affect
the outcome of critically ill patients. Lactic acidosis is the most frequent etiology and has …

Serum anion gap level predicts all-cause mortality in septic patients: A retrospective study based on the MIMIC III database

Y Zhu, Z He, Y Jin, S Zhu, W Xu, B Li… - Journal of Intensive …, 2023 - journals.sagepub.com
Purpose Sepsis is a significant threat in the intensive care unit (ICU) worldwide because it
has high morbidity and mortality rates. Early recognition and diagnosis of sepsis are …

The value of anion gap for predicting the short-term all-cause mortality of critically ill patients with cardiac diseases, based on MIMIC-III database

HR Zhang, W Tian, YJ Sun - Heart & Lung, 2022 - Elsevier
Background The association of anion gap (AG) with short-term mortality in the critically ill
patients with cardiac diseases is still not well understood. Objective To evaluate the …

A comparison of prognostic significance of strong ion gap (SIG) with other acid-base markers in the critically ill: a cohort study

KM Ho, NSH Lan, TA Williams, Y Harahsheh… - Journal of intensive …, 2016 - Springer
Background This cohort study compared the prognostic significance of strong ion gap (SIG)
with other acid-base markers in the critically ill. Methods The relationships between SIG …

Serum anion gap predicts all‐cause mortality in critically ill patients with acute kidney injury: analysis of the MIMIC‐III database

B Cheng, D Li, Y Gong, B Ying, B Wang - Disease markers, 2020 - Wiley Online Library
Background. No epidemiological study has investigated the effect of anion gap (AG) on the
prognosis of critically ill patients with acute kidney injury (AKI). Therefore, we aimed to …

Association between delta anion gap and hospital mortality for patients in cardiothoracic surgery recovery unit: a retrospective cohort study

K Xie, C Zheng, GM Wang, YF Diao, C Luo, E Wang… - BMC surgery, 2022 - Springer
Backgrounds High level of anion gap (AG) was associated with organic acidosis. This study
aimed to explore the relationship between delta AG (ΔAG= AGmax− AGmin) during first 3 …

Serum anion gap at admission as a predictor of mortality in the pediatric intensive care unit

MJ Kim, YH Kim, IS Sol, SY Kim, JD Kim, HY Kim… - Scientific reports, 2017 - nature.com
An accurate method to predict the mortality in the intensive care unit (ICU) patients has been
required, especially in children. The aim of this study is to evaluate the value of serum anion …

Serum anion gap predicts lactate poorly, but may be used to identify sepsis patients at risk for death: a cohort study

NM Mohr, JP Vakkalanka, BA Faine, B Skow… - Journal of critical …, 2018 - Elsevier
Purpose (1) To test whether serum bicarbonate or anion gap can be used to predict elevated
lactate or mortality in emergency department (ED) patients with sepsis, and (2) to define …

Serum anion gap at admission predicts all-cause mortality in critically ill patients with cerebral infarction: evidence from the MIMIC-III database

X Liu, Y Feng, X Zhu, Y Shi, M Lin, X Song, J Tu… - Biomarkers, 2020 - Taylor & Francis
Background Recent studies reported that serum anion gap could be regarded as a
prognostic biomarker for patients admitted to intensive care units. However, the association …