Objective: To investigate potential beneficial effects of donor treatment with
methylprednisolone on organ function and outcome after liver transplantation. Summary …

INTRODUCTION: Experimental studies suggest that brain death in the donor has a
significant impact on graft quality; however, there are no data correlating organ-specific …

Background. Eighty percent of donor organs come from donors who have suffered brain
trauma (brain-dead donors). This unphysiological state alters the hemodynamic and …

The majority of transplants are derived from donors who suffered from brain injury. There is
evidence that brain death causes inflammatory changes in the donor. To define the impact of …

Donor brain death has profound effects on post-transplantation graft function and survival.
We hypothesized that changes initiated in the donor influence the graft's response to …

Objective To assess the effect on the function and immunologic status of potential donor
livers of the duration of brain death combined with the presence and absence of …

PURPOSE: Corticosteroids are used to promote hemodynamic stability and reduce
inflammatory organ injury after brain death. High-dose (HD) methylprednisolone has …

Intravenous methylprednisolone is used in most liver transplant centers as first‐line therapy
of acute hepatic cellular rejection in patients who undergo liver transplant. However, no …

Background. The effects of immunosuppressive drugs on transplant tolerance have not been
extensively studied, although their effect on rejection is well established. Methods. We …

Background. Organ availability is affecting the development of liver transplantation in its
entirety, leading to transplant teams expanding the criteria for accepting organ donors. In …