Asplenic or hyposplenic (AH) individuals are particularly vulnerable to invasive infections
caused by encapsulated bacteria. Such infections have often a sudden onset and a …

Patients with functional or anatomic asplenia are at a significantly increased risk of
overwhelming infection, particularly involving the encapsulated bacteria Streptococcus …

Background Asplenic or splenectomized patients have a higher risk (ranging from 10 to 50-
fold) than the general population of developing an overwhelming post-splenectomy infection …

Background Splenectomy is associated with increased risk for bacteremia, due to impaired
clearance of bloodborne agents and to altered phagocytosis and humoral immunity. We …

The aim of the present work was to summarise in a single paper all the options for
prevention of life‐threatening infections due to encapsulated bacteria in patients with …

Overwhelming postsplenectomy sepsis is a rare but devastating and often lethal disease.
Although vaccines are available, their proper use may be questioned. Standardization of …

We determined the immunogenicity of conjugated Haemophilus influenzae type b and
pneumococcal vaccines by quantitative analysis of the antibody response in asplenic …

The spleen acts as a blood filter and lymphopoietic organ. Asplenic and hyposplenic
individuals are more susceptible to serious infections caused by encapsulated bacteria but …

Overwhelming post-splenectomy infection (OPSI) remains a long-term risk in asplenic
patients, which may be reduced by appropriate preventive measures. Specific guidelines …

Asplenic or hyposplenic patients are at risk of fulminant sepsis. This entity has a mortality of
up to 50%. The spectrum of causative organisms is evolving as are recommended …