[HTML][HTML] Historical perspective: models of Parkinson's disease
SJ Chia, EK Tan, YX Chao - International journal of molecular sciences, 2020 - mdpi.com
Parkinson's disease (PD) is the most common movement disorder with motor and nonmotor
signs. The current therapeutic regimen for PD is mainly symptomatic as the etio …
signs. The current therapeutic regimen for PD is mainly symptomatic as the etio …
Neurotoxin-induced animal models of Parkinson disease: pathogenic mechanism and assessment
XS Zeng, WS Geng, JJ Jia - ASN neuro, 2018 - journals.sagepub.com
Parkinson disease (PD) is the second most common neurodegenerative movement
disorder. Pharmacological animal models are invaluable tools to study the pathological …
disorder. Pharmacological animal models are invaluable tools to study the pathological …
[HTML][HTML] Animal models for Parkinson's disease research: trends in the 2000s
K Kin, T Yasuhara, M Kameda, I Date - International journal of molecular …, 2019 - mdpi.com
Parkinson's disease (PD) is a chronic and progressive movement disorder and the second
most common neurodegenerative disease. Although many studies have been conducted …
most common neurodegenerative disease. Although many studies have been conducted …
Animal models for preclinical Parkinson's research: an update and critical appraisal
MA Cenci, A Björklund - Progress in brain research, 2020 - Elsevier
Animal models of Parkinson's disease (PD) are essential to investigate pathogenic
pathways at the whole-organism level. Moreover, they are necessary for a preclinical …
pathways at the whole-organism level. Moreover, they are necessary for a preclinical …
[HTML][HTML] Evaluation of models of Parkinson's disease
Parkinson's disease is one of the most common neurodegenerative diseases. Animal
models have contributed a large part to our understanding and therapeutics developed for …
models have contributed a large part to our understanding and therapeutics developed for …
Neurotoxin-based models of Parkinson's disease
J Bové, C Perier - Neuroscience, 2012 - Elsevier
Animal experimentation in the Parkinson's disease (PD) field is a classic example of how the
use of animal models to study diseases can have a significant impact on human health …
use of animal models to study diseases can have a significant impact on human health …
Chemically induced models of Parkinson's disease
T Thirugnanam, K Santhakumar - … and Physiology Part C: Toxicology & …, 2022 - Elsevier
Environmental toxins are harmful substances detrimental to humans. Constant exposure to
these fatal neurotoxins can cause various neurodegenerative disorders. Although …
these fatal neurotoxins can cause various neurodegenerative disorders. Although …
Advancement in the modelling and therapeutics of Parkinson's disease
SN Rai, P Singh - Journal of chemical neuroanatomy, 2020 - Elsevier
Since the discovery of L-dopa in the middle of the 20th century (1960s), there is not any
neuroprotective therapy available although significant development has been made in the …
neuroprotective therapy available although significant development has been made in the …
[HTML][HTML] Animal models of PD: pieces of the same puzzle?
Parkinson's disease (PD) is a common neurodegenerative disorder with no known cure. The
etiology of PD is likely due, in part, to combinations of genetic susceptibilities and …
etiology of PD is likely due, in part, to combinations of genetic susceptibilities and …
Classic toxin-induced animal models of Parkinson's disease: 6-OHDA and MPTP
A Schober - Cell and tissue research, 2004 - Springer
Neurological disorders in humans can be modeled in animals using standardized
procedures that recreate specific pathogenic events and their behavioral outcomes. The …
procedures that recreate specific pathogenic events and their behavioral outcomes. The …