With the application of modern investigative technologies, cholestatic liver diseases of
genetic etiology are increasingly identified as the root cause of previously designated …

Familial intrahepatic cholestasis (FIC) comprises a group of rare cholestatic liver diseases
associated with canalicular transport defects resulting predominantly from mutations in …

With the application of modern investigative technologies, cholestatic liver diseases of
genetic etiology are increasingly identified as the root cause of previously designated …

Inherited syndromes of intrahepatic cholestasis and biliary atresia are the most common
causes of chronic liver disease and the prime indication for liver transplantation in children …

Background Jaundice is a common symptom of inherited or acquired liver diseases or a
manifestation of diseases involving red blood cell metabolism. Recent progress has …

When cholestatic liver disease is present, liver ultrasound should be performed to ascertain
if cholestasis is extrahepatic or intrahepatiic. If bile ducts appear dilated and the probability …

Introduction: Due to a peculiar age-dependent increased susceptibility, neonatal cholestasis
affects the liver of approximately 1 in every 2500 term infants. A high index of suspicion is …

Advanced cholestatic liver disease is a leading referral to pediatric liver transplant centers.
Recent advances in the genetic classification of this group of disorders promise a highly …

An American Association for the Study of Liver Diseases (AASLD)-sponsored Pediatric
Single-Topic Conference focused on the category of hepatobiliary disease collectively …

Abstract The Progressive Familial Intrahepatic Cholestasis (PFIC) disease spectrum
encompasses a variety of genetic diseases that affect the bile production and the secretion …