Regulation of inflammation and tumorigenesis by the TIPE family of phospholipid transfer proteins

JR Goldsmith, YH Chen - Cellular & molecular immunology, 2017 - nature.com
The TIPE (tumor necrosis factor-α-induced protein 8-like) family are newly described
regulators of immunity and tumorigenesis consisting of four highly homologous mammalian …

The TIPE (TNFAIP8) family in inflammation, immunity, and cancer

Y Lou, S Liu - Molecular immunology, 2011 - Elsevier
Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8 or TIPE) family are recently
identified proteins which are important for maintaining immune homeostasis. The …

TIPE family of proteins and its implications in different chronic diseases

D Bordoloi, K Banik, B Shabnam… - International journal of …, 2018 - mdpi.com
The tumor necrosis factor-α-induced protein 8-like (TIPE/TNFAIP8) family is a recently
identified family of proteins that is strongly associated with the regulation of immunity and …

[HTML][HTML] TNFAIP8: inflammation, immunity and human diseases

S Niture, J Moore, D Kumar - Journal of cellular immunology, 2019 - ncbi.nlm.nih.gov
Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8/TIPE) family proteins are
known to be involved in maintaining immune homeostasis. The TIPE family contains four …

Identical expression profiling of human and murine TIPE3 protein reveals links to its functions

J Cui, C Hao, W Zhang, J Shao… - … of Histochemistry & …, 2015 - journals.sagepub.com
Tumor necrosis factor-alpha-induced protein-8 like-3 (TNFAIP8L3, TIPE3) is a newly
discovered member of TNFAIP8 family and regarded as a lipid second messenger transfer …

Regulatory roles of tumor necrosis factor-α-induced protein 8 like-protein 2 in inflammation, immunity and cancers: A review

Z Gu, X Cui, P Sun, X Wang - Cancer management and research, 2020 - Taylor & Francis
Tumor necrosis factor-alpha (TNF-α)-induced protein 8 (TNFAIP8/TIPE) family, including
TNFAIP8 (TIPE), TNFAIP8 like-protein 1 (TNFAIP8L1/TIPE1), TNFAIP8 like-protein 2 …

TIPE3 is the transfer protein of lipid second messengers that promote cancer

SA Fayngerts, J Wu, CL Oxley, X Liu, A Vourekas… - Cancer cell, 2014 - cell.com
More than half of human cancers have aberrantly upregulated phosphoinositide signals; yet
how phospholipid signals are controlled during tumorigenesis is not fully understood. We …

The unique expression profile of human TIPE2 suggests new functions beyond its role in immune regulation

L Zhang, Y Shi, Y Wang, F Zhu, Q Wang, C Ma… - Molecular …, 2011 - Elsevier
TIPE2 (tumor necrosis factor-α-induced protein 8-like 2, or TNFAIP8L2) is a newly identified
negative regulator of innate and adaptive immunity. TIPE2 deficiency in mice leads to …

The expression of TIPE1 in murine tissues and human cell lines

J Cui, G Zhang, C Hao, Y Wang, Y Lou, W Zhang… - Molecular …, 2011 - Elsevier
Members of the tumor necrosis factor-alpha-induced protein-8 (TNFAIP8 or TIPE) family play
important roles in immune homeostasis and cancer. TIPE1 (TNFAIP8-like 1) is a new …

Novel tumor necrosis factor-α induced protein eight (TNFAIP8/TIPE) family: Functions and downstream targets involved in cancer progression

G Padmavathi, K Banik, J Monisha, D Bordoloi… - Cancer letters, 2018 - Elsevier
The tumor necrosis factor (TNF)-α-induced protein 8 (TNFAIP8/TIPE) family is a death
effector domain (DED)-containing protein family with four identified members: TNFAIP8 …