Genetics and epigenetics in allergic rhinitis

BY Choi, M Han, JW Kwak, TH Kim - Genes, 2021 - mdpi.com
The pathogenesis of allergic rhinitis is associated with genetic, environmental, and
epigenetic factors. Genotyping of single nucleotide polymorphisms (SNPs) is an advanced …

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

J Waage, M Standl, JA Curtin, LE Jessen, J Thorsen… - Nature …, 2018 - nature.com
Allergic rhinitis is the most common clinical presentation of allergy, affecting 400 million
people worldwide, with increasing incidence in westernized countries,. To elucidate the …

Epigenetics and the environment in airway disease: asthma and allergic rhinitis

A Long, B Bunning, V Sampath, RH DeKruyff… - Epigenetics in Allergy …, 2020 - Springer
Asthma and rhinitis are complex, heterogeneous diseases characterized by chronic
inflammation of the upper and lower airways. While genome-wide association studies …

Risk factors of allergic rhinitis: genetic or environmental?

DY Wang - Therapeutics and clinical risk management, 2005 - Taylor & Francis
Allergic diseases such as allergic rhinitis represent a global health problem, affecting 10%–
25% of the world population. There is clear evidence to support the concept that allergic …

Discovering susceptibility genes for allergic rhinitis and allergy using a genome-wide association study strategy

J Li, Y Zhang, L Zhang - Current opinion in allergy and clinical …, 2015 - journals.lww.com
Large-scale genome-wide association strategies are underway to discover new
susceptibility variants for allergic rhinitis and allergic phenotypes. Characterization of the …

Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis

S Bunyavanich, EE Schadt, BE Himes, J Lasky-Su… - BMC medical …, 2014 - Springer
Background Allergic rhinitis is a common disease whose genetic basis is incompletely
explained. We report an integrated genomic analysis of allergic rhinitis. Methods We …

Allergic rhinitis–a total genome-scan for susceptibility genes suggests a locus on chromosome 4q24-q27

A Haagerup, T Bjerke, PO Schøitz… - European Journal of …, 2001 - nature.com
Allergic rhinitis is a common disease of complex inheritance and is characterised by
mucosal inflammation caused by allergen exposure. The genetics of closely related …

The search for genetic variants and epigenetics related to asthma

SH Lee, JS Park, CS Park - Allergy, asthma & immunology …, 2011 - synapse.koreamed.org
For the past two decades, a huge number of genetic studies have been conducted to identify
the genetic variants responsible for asthma risk. Several types of genetic and genomic …

Genome-wide association studies of allergic diseases

M Tamari, S Tanaka, T Hirota - Allergology International, 2013 - jstage.jst.go.jp
Allergic diseases are complex diseases caused by a combination of genetic and
environmental factors. To determine the genetic components of these diseases and to …

Unraveling the genetic basis of asthma and allergic diseases

JF Meng, LJ Rosenwasser - Allergy, asthma & immunology …, 2010 - synapse.koreamed.org
Asthma and allergic diseases are believed to be complex genetic diseases which may result
from the interaction of multiple genetic factors and environmental stimuli. In past decades …