[HTML][HTML] May a different kinetic mode explain the high efficacy/safety profile of inhaled budesonide?
R Brattsand, O Selroos - Pulmonary Pharmacology & Therapeutics, 2022 - Elsevier
The claimed functional basis for ICSs in asthma and COPD is airway selectivity, attained by
inhaling a potent, lipophilic compound with long local dissolution/absorption time. The …
inhaling a potent, lipophilic compound with long local dissolution/absorption time. The …
Budesonide Attains Its Wide Clinical Profile by Alternative Kinetics
R Brattsand, O Selroos - Pharmaceuticals, 2024 - mdpi.com
The introduction of inhaled corticosteroids (ICSs) changed over a few decades the treatment
focus of mild-to-moderate asthma from bronchodilation to reduction in inflammation. This …
focus of mild-to-moderate asthma from bronchodilation to reduction in inflammation. This …
Budesonide/formoterol in the treatment of asthma
D Hodgson, K Mortimer, T Harrison - Expert review of respiratory …, 2010 - Taylor & Francis
Budesonide and formoterol are available in a combined inhaler that offers therapeutic
advantages in the treatment of asthma. The rapid onset of bronchodilation seen with …
advantages in the treatment of asthma. The rapid onset of bronchodilation seen with …
Budesonide/formoterol: a review of its use as maintenance and reliever inhalation therapy in asthma
PL McCormack, KA Lyseng-Williamson - Drugs, 2007 - Springer
The use of combination budesonide/formoterol dry powder inhaler (Symbicort®
Turbuhaler®) for both daily maintenance therapy and as-needed relief of breakthrough …
Turbuhaler®) for both daily maintenance therapy and as-needed relief of breakthrough …
Budesonide/formoterol for the treatment of asthma
R Buhl - Expert Opinion on Pharmacotherapy, 2003 - Taylor & Francis
Budesonide/formoterol (Symbicort®, AstraZeneca plc) is a novel treatment for asthma,
combining an inhaled corticosteroid–budesonide, and a long-acting β2-agonist–formoterol …
combining an inhaled corticosteroid–budesonide, and a long-acting β2-agonist–formoterol …
Budesonide/formoterol: a review of its use in asthma
DR Goldsmith, GM Keating - Drugs, 2004 - Springer
Budesonide and formoterol have been combined in a single dry powder device, Symbicort®
Turbuhaler®(budesonide/formoterol 160/9–640/18 μg/day), in an effort to simplify asthma …
Turbuhaler®(budesonide/formoterol 160/9–640/18 μg/day), in an effort to simplify asthma …
Efficacy and safety of high‐dose budesonide/formoterol (Symbicort®) compared with budesonide administered either concomitantly with formoterol or alone in …
Objective and background: Budesonide/formoterol 160/4.5 µg, two inhalations bd, is an
effective and well‐tolerated maintenance therapy for patients not controlled on inhaled …
effective and well‐tolerated maintenance therapy for patients not controlled on inhaled …
Differences in the pharmacodynamics of budesonide/formoterol and salmeterol/fluticasone reflect differences in their therapeutic usefulness in asthma
B Lindmark - Therapeutic Advances in Respiratory Disease, 2008 - journals.sagepub.com
Although the available inhaled corticosteroid (ICS)/long-acting β 2-agonist (LABA)
combinations principally work in a similar fashion, they differ in several important ways …
combinations principally work in a similar fashion, they differ in several important ways …
Efficacy of budesonide in moderate to severe asthma
EJ O'Connell - Clinical therapeutics, 2002 - Elsevier
Background: The worldwide prevalence of asthma is increasing by∼ 50% per decade.
Budesonide is one of several inhaled corticosteroids available for the treatment of asthma …
Budesonide is one of several inhaled corticosteroids available for the treatment of asthma …
Preclinical properties of budesonide: Translation to the clinical setting
DS Pearlman - Clinical therapeutics, 2003 - Elsevier
Background: Since the introduction of inhaled corticosteroids (ICSs) nearly 30 years ago, the
management of asthma has been transformed. It is now understood that asthma is primarily …
management of asthma has been transformed. It is now understood that asthma is primarily …