Well-done meat intake, heterocyclic amine exposure, and cancer risk
High intake of meat, particularly red and processed meat, has been associated with an
increased risk of a number of common cancers such as breast, colorectum, and prostate in …
increased risk of a number of common cancers such as breast, colorectum, and prostate in …
An epidemiologic approach to studying heterocyclic amines
R Sinha - … Research/Fundamental and Molecular Mechanisms of …, 2002 - Elsevier
Diets containing substantial amounts of red meat may increase the risk of colorectal,
pancreatic, breast, prostate, and renal cancer. The association with red meat intake may be …
pancreatic, breast, prostate, and renal cancer. The association with red meat intake may be …
Heterocyclic amines in cooked meat products, shortcomings during evaluation, factors influencing formation, risk assessment and mitigation strategies
At this point in time, the evidence of a link between well-done meat intake and the incidence
of cancer is stronger than it was 20 years ago. Several cohort and case-control studies have …
of cancer is stronger than it was 20 years ago. Several cohort and case-control studies have …
Heterocyclic amine content of cooked meat and risk of prostate cancer
AE Norrish, LR Ferguson, MG Knize… - Journal of the …, 1999 - academic.oup.com
BACKGROUND: Some epidemiologic studies have described positive associations between
prostate cancer risk and meat consumption, but underlying mechanisms have not been …
prostate cancer risk and meat consumption, but underlying mechanisms have not been …
Red meat-derived heterocyclic amines increase risk of colon cancer: a population-based case-control study
DS Helmus, CL Thompson, S Zelenskiy… - Nutrition and …, 2013 - Taylor & Francis
Formation of mutagenic heterocyclic amines (HCAs) and polycyclic aromatic hydrocarbons
(PAHs) is one pathway believed to drive the association of colon cancer with meat …
(PAHs) is one pathway believed to drive the association of colon cancer with meat …
Heterocyclic amine content in beef cooked by different methods to varying degrees of doneness and gravy made from meat drippings
R Sinha, N Rothman, CP Salmon, MG Knize… - Food and Chemical …, 1998 - Elsevier
Meats cooked at high temperatures sometimes contain heterocyclic amines (HCAs) that are
known mutagens and animal carcinogens, but their carcinogenic potential in humans has …
known mutagens and animal carcinogens, but their carcinogenic potential in humans has …
Dietary intake of heterocyclic amines, meat-derived mutagenic activity, and risk of colorectal adenomas
R Sinha, M Kulldorff, WH Chow, J Denobile… - … Biomarkers & Prevention, 2001 - AACR
Meats cooked well-done by high temperature techniques produce mutagenic compounds
such as heterocyclic amines (HCAs), but the amounts of these compounds vary by cooking …
such as heterocyclic amines (HCAs), but the amounts of these compounds vary by cooking …
Well-done meat intake and the risk of breast cancer
W Zheng, DR Gustafson, D Moore… - Journal of the …, 1998 - academic.oup.com
Background: Heterocyclic amines, mutagens formed in meats cooked at high temperatures,
have been demonstrated as mammary carcinogens in animals. We conducted a nested …
have been demonstrated as mammary carcinogens in animals. We conducted a nested …
Meat‐related mutagens/carcinogens in the etiology of colorectal cancer
AJ Cross, R Sinha - Environmental and molecular mutagenesis, 2004 - Wiley Online Library
Diets containing substantial amounts of red or preserved meats may increase the risk of
various cancers, including colorectal cancer. This association may be due to a combination …
various cancers, including colorectal cancer. This association may be due to a combination …
Cancer risk of heterocyclic amines in cooked foods: an analysis and implications for research
DW Layton, KT Bogen, MG Knize, FT Hatch… - …, 1995 - academic.oup.com
Heterocyclic amines (HAs) are formed as pyrolysis products during the cooking of
meats/fish. These substances are potent mutagens in the Ames/Salmonella assay and are …
meats/fish. These substances are potent mutagens in the Ames/Salmonella assay and are …
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