Efforts to determine why new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) variants demonstrate improved fitness have been limited to analyzing mutations in the …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant
contains extensive sequence changes relative to the earlier-arising B. 1, B. 1.1, and Delta …

Viruses evolve as a result of mutation (misincorporations, insertions or deletions, and
recombination) and natural selection for favorable traits such as more efficient viral …

The spike aspartic acid–614 to glycine (D614G) substitution is prevalent in global severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains, but its effects on viral …

Recently, a novel isolate of the SARS-CoV-2 virus carrying a point mutation in the Spike
protein (D614G) has emerged and rapidly surpassed others in prevalence, including the …

Persistent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have
been reported in immune-compromised individuals and people undergoing immune …

Repeated emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants with increased fitness underscores the value of rapid detection and characterization …

The importance of understanding SARS-CoV-2 evolution cannot be overlooked. Recent
studies confirm that natural selection is the dominating mechanism of SARS-CoV-2 …

Research activities with infectious severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) are currently permitted only under biosafety level 3 (BSL3) containment. Here, we …

Recent reports suggest that some SARS-CoV-2 genetic variants, such as B. 1.1. 7, might be
more transmissible and are quickly spreading around the world. As the emergence of more …