A novel time-resolved fluoroimmunoassay based on magnetic microspheres method for detecting antibodies against the phospholipase A2 receptor

T Li, Q Wu, X Yang, Y Liu, B Lin, X Zhou, Y Wang… - Analytical …, 2021 - pubs.rsc.org
Background: the level of serum antibodies against the M-type phospholipase A2 receptor
(anti-PLA2R-IgG) is closely related to the disease activity of idiopathic membranous …

A novel time-resolved fluoroimmunoassay for the quantitative detection of antibodies against the phospholipase A2 receptor

B Huang, L Wang, Y Zhang, J Zhang, Q Zhang… - Scientific reports, 2017 - nature.com
A highly sensitive time-resolved fluoroimmunoassay (TRFIA) was developed to quantify
serum antibodies against the phospholipase A2 receptor (anti-PLA2R-IgG) for differential …

Quantitative detection of anti-PLA2R antibodies targeting different epitopes and its clinical application in primary membranous nephropathy

Y Qin, Q Wu, H Sheng, T Li, X Liu, X Yang… - Clinical Chemistry and …, 2023 - degruyter.com
Objectives This study aimed to establish time-resolved fluorescence immunoassays to
quantitatively detect the autoantibodies targeting different epitopes of M-type phospholipase …

[HTML][HTML] Comparison of performance and clinical utility of different methods for detecting anti-PLA2R antibody

T Wang, M Wang, W Yu, H Li, Z Zhao, J Shang - Clinica Chimica Acta, 2023 - Elsevier
Objectives This study aimed to compare the performance of enzyme-linked immunosorbent
assay (ELISA) and magnetic particle chemiluminescence immunoassay (MP-CLIA) for …

Establishment and application of an immunoassay for the simultaneous detection of IgG and its subtype IgG4 autoantibodies against M-type phospholipase A2 …

T Li, Q Wu, X Yang, Y Zhang, X Zhou, H Sheng… - Clinical …, 2021 - Elsevier
Background The renal biopsy is an accurate and reliable gold standard for membranous
nephropathy (MN) diagnosis. However, it is an invasive procedure involving the risk of …

[HTML][HTML] Development of a standardized chemiluminescence immunoassay for the detection of autoantibodies against human M-type phospholipase A2 receptor in …

C Dähnrich, S Saschenbrecker, I Gunnarsson… - Kidney International …, 2020 - Elsevier
Introduction Autoantibodies against the M-type phospholipase A2 receptor (PLA2R) are
important markers in the diagnosis and monitoring of primary membranous nephropathy …

Ultrasensitive quantitation of anti-phospholipase A2 receptor antibody as a diagnostic and prognostic indicator of idiopathic membranous nephropathy

Q Zhang, B Huang, X Liu, B Liu, Y Zhang, Z Zhang… - Scientific Reports, 2017 - nature.com
Anti-phospholipase A2 receptor antibody (PLA2R-Ab) is useful for affirming the diagnosis of
idiopathic membranous nephropathy (IMN). Time-resolved fluoroimmunoassay (TRFIA) is …

Rapid, quantitative, and high-sensitivity detection of anti-phospholipase A2 receptor antibodies using a novel CdSe/ZnS-based fluorescence immunosorbent assay

C Li, M Qian, Q Hong, X Xin, Z Sun, Y Li, B Tang… - Scientific Reports, 2021 - nature.com
Autoantibodies against M-type phospholipase A2 receptor (PLA2R) serve as specific
biomarkers for idiopathic membranous nephropathy (IMN), and its quantification helps …

[HTML][HTML] Phospholipase A2 receptor antibody IgG4 subclass improves sensitivity and specificity in the diagnosis of idiopathic membranous nephropathy

B Huang, Y Zhang, L Wang, W Xu, J Zhang… - Kidney and Blood …, 2019 - karger.com
Aims: The aim of this study was to develop a new method for detecting anti-phospholipase
A2 receptor-IgG4 to improve the sensitivity and specificity in the diagnosis of idiopathic …

Receptor antibody time‐resolved A2 phospholipase bead immunochromatography and its application in idiopathic membranous nephropathy

B Huang, X Yang, W Zhang, J Wu, P Liu… - Journal of Clinical …, 2020 - Wiley Online Library
Objective To detect phospholipase A2 receptor (PLA2R) antibody by established time‐
resolved fluorescent bead immunochromatographic assay. Methods The reaction time of …