Comparison of mixed-model approaches for association mapping

B Stich, J Möhring, HP Piepho, M Heckenberger… - Genetics, 2008 - academic.oup.com
Association-mapping methods promise to overcome the limitations of linkage-mapping
methods. The main objectives of this study were to (i) evaluate various methods for …

[HTML][HTML] Comparison of biometrical models for joint linkage association mapping

T Würschum, W Liu, M Gowda, HP Maurer, S Fischer… - Heredity, 2012 - nature.com
Joint linkage association mapping (JLAM) combines the advantages of linkage mapping
and association mapping, and is a powerful tool to dissect the genetic architecture of …

[HTML][HTML] Variation explained in mixed-model association mapping

G Sun, C Zhu, MH Kramer, SS Yang, W Song… - Heredity, 2010 - nature.com
Genomic mapping of complex traits across species demands integrating genetics and
statistics. In particular, because it is easily interpreted, the R 2 statistic is commonly used in …

Genome-wide association mapping: a case study in bread wheat (Triticum aestivum L.)

K Neumann, B Kobiljski, S Denčić, RK Varshney… - Molecular …, 2011 - Springer
Association-based trait mapping is an innovative methodology based on linkage
disequilibrium. Studies in plants, especially in cereals, are rare. A genome-wide association …

Efficient multiple-trait association and estimation of genetic correlation using the matrix-variate linear mixed model

NA Furlotte, E Eskin - Genetics, 2015 - academic.oup.com
Multiple-trait association mapping, in which multiple traits are used simultaneously in the
identification of genetic variants affecting those traits, has recently attracted interest. One …

Simulation appraisal of the adequacy of number of background markers for relationship estimation in association mapping

J Yu, Z Zhang, C Zhu, DA Tabanao… - The Plant …, 2009 - Wiley Online Library
Complex trait dissection through association mapping provides a powerful complement to
traditional linkage analysis. The genetic structure of an association mapping panel can be …

[HTML][HTML] Comparing different statistical models and multiple testing corrections for association mapping in soybean and maize

AS Kaler, JD Gillman, T Beissinger… - Frontiers in plant …, 2020 - frontiersin.org
Association mapping (AM) is a powerful tool for fine mapping complex trait variation down to
nucleotide sequences by exploiting historical recombination events. A major problem in AM …

Genome-wide association mapping of three important traits using bread wheat elite breeding populations

J Bordes, E Goudemand, L Duchalais, L Chevarin… - Molecular …, 2014 - Springer
The exponential development of molecular markers enables a more effective study of the
genetic architecture of traits of economic importance, like test weight in wheat (Triticum …

[HTML][HTML] Comparison of mixed-model approaches for association mapping in rapeseed, potato, sugar beet, maize, and Arabidopsis

B Stich, AE Melchinger - BMC genomics, 2009 - Springer
Background In recent years, several attempts have been made in plant genetics to detect
QTL by using association mapping methods. The objectives of this study were to (i) evaluate …

Recovering power in association mapping panels with variable levels of linkage disequilibrium

R Rincent, L Moreau, H Monod, E Kuhn… - Genetics, 2014 - academic.oup.com
Association mapping has permitted the discovery of major QTL in many species. It can be
applied to existing populations and, as a consequence, it is generally necessary to take into …