The mechanisms underlying predisposition to alcohol abuse and alcoholism are poorly
understood. In this study, we evaluated the role of cannabinoid (CB1) receptors in (i) …

Recent advances in the understanding of the neurobiological basis of alcohol dependence
suggest that the endocannabinoid system may play a key role in the reinforcing effects of …

Aims: The aim of this study was to examine the effects of chronic ethanol consumption in
cannabinoid CB1 receptor gene expression in Wistar rats. Methods: Rats were exposed to a …

Although many people drink alcohol regularly, only some become addicted. Several studies
have shown that genetic and environmental factors contribute to individual differences in the …

Cannabinoids and alcohol activate the same reward pathways, and the cannabinoid CB 1
receptor system plays an important role in regulating the positive reinforcing properties of …

This study examines the role of the cannabinoid CB2 receptor (CB2r) on the vulnerability to
ethanol consumption. The time‐related and dose‐response effects of ethanol on rectal …

Consumers of marijuana typically feel a strong, compulsive desire to consume food.
Although past research revealed that the CB1 cannabinoid receptor is a potent regulator of …

Cannabinoids and ethanol activate the same reward pathways, and recent advances in the
understanding of the neurobiological basis of alcoholism suggest that the CB 1 receptor …

The present review evaluates the evidence that the endocannabinoid system plays in the
development of tolerance to alcohol. The identification of a G-protein-coupled receptor …

The endocannabinoid system is involved in a variety of effects of drugs of misuse, and
blockade of the cannabinoid CB1 receptor by selective antagonists elicits marked reductions …