Lipoprotein (a) hyperlipidemia as cardiovascular risk factor: pathophysiological aspects

G Schmitz, E Orsó - Clinical research in cardiology supplements, 2015 - Springer
Abstract Lipoprotein (a)[Lp (a)] is a modified LDL particle with an additional apolipoprotein
[apo (a)] protein covalently attached by a thioester bond. Multiple isoforms of apo (a) exist …

Lipoprotein (a)–Marker for cardiovascular risk and target for lipoprotein apheresis

R Klingel, F Heigl, V Schettler, E Roeseler… - Atherosclerosis …, 2019 - Elsevier
Abstract Lipoprotein (a)(Lp (a)) consists of an LDL particle whose apolipoprotein B (apoB) is
covalently bound to apolipoprotein (a)(apo [a]). An increased Lp (a) concentration is a …

Lipoprotein (a)

M Koschinsky, SM Marcovina - Clinical lipidology: a companion …, 2009 - books.google.com
Although numerous studies since the 1960s have identified increased plasma
concentrations of lipoprotein (a)[Lp (a)] as a risk factor for coronary heart disease (CHD), the …

Lipoprotein (a) in health and disease

F Kronenberg, A Steinmetz, GM Kostner… - Critical reviews in …, 1996 - Taylor & Francis
Abstract Lipoprotein (a)[Lp (a)] represents an LDL-like particle to which the Lp (a)-specific
apolipoprotein (a) is linked via a disulfide bridge. It has gained considerable interest as a …

Novel insights into Lp (a) physiology and pathogenicity: more questions than answers?

ML Koschinsky - … -Drug Targets (Formerly Current Drug Targets …, 2006 - ingentaconnect.com
Lipoprotein (a)(Lp (a)) is of interest to both basic researchers who endeavour to understand
the mechanism of action of this unique lipoprotein, as well as to clinicians who are interested …

Molecular, population, and clinical aspects of lipoprotein (a): a bridge too far?

NC Ward, KM Kostner, DR Sullivan, P Nestel… - Journal of clinical …, 2019 - mdpi.com
There is now significant evidence to support an independent causal role for lipoprotein
(a)(Lp (a)) as a risk factor for atherosclerotic cardiovascular disease. Plasma Lp (a) …

Lipoprotein (a) as a cardiovascular risk factor

AM Scanu - Trends in Cardiovascular Medicine, 1991 - Elsevier
Abstract Lipoprotein (a)[Lp (a)] is a class of lipoprotein particles having the lipid composition
of plasma low-density lipoprotein (LDL), but with a distinct protein moiety comprised of two …

Lipoprotein (a) as a cardiovascular risk factor: current status

BG Nordestgaard, MJ Chapman, K Ray… - European heart …, 2010 - academic.oup.com
Aims The aims of the study were, first, to critically evaluate lipoprotein (a)[Lp (a)] as a
cardiovascular risk factor and, second, to advise on screening for elevated plasma Lp (a), on …

Lipoprotein (a): A missing culprit in the management of athero‐thrombosis?

G Ferretti, T Bacchetti, TP Johnston… - Journal of Cellular …, 2018 - Wiley Online Library
Lipoprotein (a) Lp (a) is a cholesterol‐rich, LDL‐like particle that is independently
associated with an increased risk for ischemic heart disease, atherosclerosis, thrombosis …

Lipoprotein (a): a genetic risk factor for premature coronary heart disease

AM Scanu - JAMA, 1992 - jamanetwork.com
Lipoprotein (a)(Lp [a]) can be defined as a lipoprotein particle having as a protein moiety
apolipoprotein B-100 (the protein associated with low-density lipoprotein) disulfide-linked to …