Interleukin 6 (IL-6) belongs to a broad class of cytokines involved in the regulation of various
homeostatic and pathological processes. These activities range from regulating embryonic …

In the last several decades, the number of people dying from cancer-related deaths has not
reduced significantly despite phenomenal advances in the technologies related to diagnosis …

Inflammatory responses play pivotal roles in cancer development, including tumor initiation,
promotion, progression, and metastasis. Cytokines are now recognized as important …

Within the tumor microenvironment, IL-6 signaling is generally considered a malevolent
player, assuming a dark visage that promotes tumor progression. Chronic IL-6 signaling is …

Interleukin-6 (IL-6) is a multifunctional cytokine which plays an important role in a wide
range of biologic activities in different types of cell including tumor cells. IL-6 is involved in …

Interleukin (IL)-6 is a pro-inflammatory cytokine that produces multifunctional effects.
Deregulated IL-6 production and signaling are associated with chronic inflammatory …

Abstract Interleukin-6 (IL-6) is a cytokine present in tumor microenvironment. Elevated level
of IL-6 is associated with cancer cell proliferation, angiogenesis and metastasis through …

Inflammation is an important component of the tumor microenvironment. IL‐1 is an
inflammatory cytokine which plays a key role in carcinogenesis and tumor progression. IL‐1 …

Interleukin-6 (IL-6) is a pleiotropic cytokine that activates a classic signalling pathway upon
binding to its membrane-bound receptor (IL-6R). Alternatively, IL-6 may 'trans-signal'in a …

Abstract Interleukin‐6 (IL‐6) plays a major role in the response to injury or infection and is
involved in the immune response, inflammation, and hematopoiesis. Its deregulation …