Chlamydia trachomatis genome is predicted to encode a type III secretion system consisting
of more than 40 open reading frames (ORFs). To test whether these ORFs are expressed …

We have previously shown that individuals infected with Chlamydia trachomatis can develop
a robust antibody response to a Chlamydia type III secretion effector protein called Tarp and …

Chlamydia trachomatis imposes serious health problems and causes infertility. Because of
asymptomatic onset, it often escapes antibiotic treatment. Therefore, vaccines offer a better …

Chlamydia trachomatis infections in women are often asymptomatic and if left untreated can
lead to significant late sequelae including pelvic inflammatory disease and tubal factor …

A comprehensive proteomic screening technology was previously used to characterize T
cell responses to Chlamydia trachomatis infection. In this study, we demonstrated that T cells …

Chlamydia spp. utilize multiple secretion systems, including the type III secretion system
(T3SS), to deploy host-interactive effector proteins into infected host cells. Elucidation of …

Using antibodies raised with C. trachomatis fusion proteins, we localized a hypothetical
protein encoded by the ORF ct622 in the cytoplasm of C. trachomatis-infected mammalian …

To search for optimal immunization conditions for inducing protective immunity against
upper genital tract pathologies caused by chlamydial intravaginal infection, we compared …

The available chlamydial genome sequences have made it possible to comprehensively
analyze host responses to all chlamydial proteins, which is essential for further …

Chlamydia trachomatis infections can lead to severe chronic complications, including
trachoma, ectopic pregnancy, and infertility. The only effective approach to disease control is …