[Purpose] The aim of this study was to investigate the effects of regular treadmill exercise on
skeletal muscle Rictor-Akt and mTOR-Raptor-S6K1 signaling pathway in high-fat diet …

[Purpose] The purpose of this study was to investigate the effect of exercise and dietary
change on obesity and insulin resistance and mTOR signaling protein levels in skeletal …

Obesity and insulin resistance are rapidly expanding public health problems. These
disturbances are related to many diseases, including heart pathology. Acting through the …

The crosstalk between mTORC1/S6K1 signaling and AMPK is emerging as a powerful and
highly regulated way to gauge cellular energy and nutrient content. The aim of the current …

The current dogma is that the muscle adaptation to resistance exercise is blunted when
combined with endurance exercise. The suggested mechanism (based on rodent …

Short-term (5–10 days) calorie restriction (CR) downregulates muscle protein synthesis, with
consumption of a high protein-based diet attenuating this decline. Benefit of increase protein …

Obesity is associated with myocardial insulin resistance and impairment of the mammalian
target of rapamycin (mTOR) signaling pathway. The activation of the mTOR cascade by …

The aim of this study was to determine the effect of 14 days of 5-aminoimidazole-4-
carboxamide-1β-4-ribofuranoside (AICAR) treatment on mammalian target of rapamycin …

Concurrent training, a combination of endurance (EE) and resistance exercise (RE)
performed in succession, may compromise the muscle hypertrophic adaptations induced by …

Resistance exercise (RE) activates signalling by the mammalian target of rapamycin
(mTOR) and it has been suggested that rapamycin-sensitive mTOR signalling controls RE …