The behaviour of lactotroph tumours varies between benign tumours, those cured by
treatment, and that of aggressive tumours, and carcinomas with metastasis. Identification of …

Prolactin-secreting tumors (prolactinomas) represent the most common pituitary tumor type,
accounting for 47–66% of functional pituitary tumors. Prolactinomas are usually benign and …

A small subset of lactotroph adenomas is resistant to dopamine agonists (DA) and can also
demonstrate aggressive or even malignant behavior. The implicated mechanisms are not …

Purpose Aggressive prolactinomas are defined as radiologically invasive tumors which
cannot be cured by surgery, and that have an unusually rapid rate of tumor growth despite …

In recent years the demonstration that human pituitary adenomas are monoclonal in origin
provides further evidence that pituitary neoplasia arise from the replication of a single …

BACKGROUND/AIMS: Prolactinomas are the most common tumors of the pituitary gland.
Only few studies have documented gender-related differences in the growth and …

Objective To explore the basis of the gender-based differences in endocrine and surgical
findings in patients with prolactinoma (prolactin cell adenoma) as well as in their clinical …

Prolactinoma is the most common pituitary tumour in adults. Macroprolactinomas,
particularly in men, may occasionally exhibit a very aggressive clinical course as evidenced …

Sex-related differences have been reported in various cancers, in particular men with
lactotroph tumors have a worse prognosis than women. While the underlying mechanism of …

Pituitary carcinomas are extremely rare. In general, the initial clinical, biochemical, and
histological characteristics are of minimal utility in distinguishing benign adenomas from …