Whole Exome-Wide Association Identifies Rare Variants in GALNT9 Associated with Middle Eastern Papillary Thyroid Carcinoma Risk

R Bu, AK Siraj, S Azam, K Iqbal, Z Qadri, M Al-Rasheed… - Cancers, 2023 - mdpi.com
Simple Summary This study targeted the identification of rare variants in Middle Eastern
papillary thyroid carcinoma (PTC) through an exome-wide association study. It was found …

[HTML][HTML] rs965513 polymorphism as a common risk marker is associated with papillary thyroid cancer

F Wang, D Yan, X Ji, J Han, M Chen, H Qiao, S Zhang - Oncotarget, 2016 - ncbi.nlm.nih.gov
Papillary thyroid cancer (PTC) is the most common type of thyroid cancer. With the rapid
development of genome-wide association studies (GWAS), many genome variants …

Variants in LRRC34 reveal distinct mechanisms for predisposition to papillary thyroid carcinoma

DF Comiskey Jr, H He, S Liyanarachchi… - Journal of Medical …, 2020 - jmg.bmj.com
Background Papillary thyroid carcinoma (PTC) demonstrates high heritability and a low
somatic mutation burden relative to other cancers. Therefore, the genetic risk predisposing …

Papillary thyroid carcinoma: association between germline DNA variant markers and clinical parameters

J Jendrzejewski, S Liyanarachchi, R Nagy, L Senter… - Thyroid, 2016 - liebertpub.com
Background: Papillary thyroid cancer (PTC) is reported to be highly heritable in
epidemiological studies. Genome-wide association studies (GWAS) have uncovered several …

Association of polygenic score with tumor molecular subtypes in papillary thyroid carcinoma

JR Wang, ME Zafereo, W Wang… - The Journal of Clinical …, 2024 - academic.oup.com
Context Genome-wide association studies have identified germline variants associated with
elevated PTC risk. It is also known that somatic driver mutations contribute to PTC …

Genome-wide association and expression quantitative trait loci studies identify multiple susceptibility loci for thyroid cancer

HY Son, Y Hwangbo, SK Yoo, SW Im, SD Yang… - Nature …, 2017 - nature.com
Thyroid cancer is the most common cancer in Korea. Several susceptibility loci of
differentiated thyroid cancer (DTC) were identified by previous genome-wide association …

Novel somatic alterations underlie Chinese papillary thyroid carcinoma

C Yang, W Xu, J Gong, Z Liu, D Cui - Cancer Biomarkers, 2020 - content.iospress.com
To characterize the somatic alterations of papillary thyroid carcinomas (PTC) in Chinese
patients, we performed the next-generation-sequencing (NGS) study of the tumor-normal …

Fine mapping of 14q13 reveals novel variants associated with different histological subtypes of papillary thyroid carcinoma

J Jendrzejewski, S Liyanarachchi… - … journal of cancer, 2019 - Wiley Online Library
The first two genome wide association studies (GWAS) of papillary thyroid carcinoma (PTC)
detected five variants associated with PTC. Two of them (rs944289 and rs116909374) are …

Confirmation of papillary thyroid cancer susceptibility loci identified by genome-wide association studies of chromosomes 14q13, 9q22, 2q35 and 8p12 in a Chinese …

YL Wang, SH Feng, SC Guo, WJ Wei, DS Li… - Journal of medical …, 2013 - jmg.bmj.com
Background Five single nucleotide polymorphisms (SNPs) were previously reported to be
associated with thyroid cancer in European populations in two genome-wide association …

Cumulative risk impact of five genetic variants associated with papillary thyroid carcinoma

S Liyanarachchi, A Wojcicka, W Li, M Czetwertynska… - Thyroid, 2013 - liebertpub.com
Background: Two recent genome-wide association studies (GWASs) identified five single
nucleotide polymorphisms (SNPs; rs965513, rs944289, rs966423, rs2439302, and …