Oral administration of lysozyme protects against injury of ileum via modulating gut microbiota dysbiosis after severe traumatic brain injury

W Yang, C Xi, H Yao, Q Yuan, J Zhang… - Frontiers in Cellular …, 2024 - frontiersin.org
Objective The current study sought to clarify the role of lysozyme-regulated gut microbiota
and explored the potential therapeutic effects of lysozyme on ileum injury induced by severe …

[HTML][HTML] Inulin supplementation mitigates gut dysbiosis and brain impairment induced by mild traumatic brain injury during chronic phase

LM Yanckello, B Fanelli, S McCulloch… - Journal of cellular …, 2022 - ncbi.nlm.nih.gov
Mild traumatic brain injury (mTBI) has been shown to acutely alter the gut microbiome
diversity and composition, known as dysbiosis, which can further exacerbate metabolic and …

Traumatic brain injury induces gastrointestinal dysfunction and dysbiosis of gut microbiota accompanied by alterations of bile acid profile

W You, Y Zhu, A Wei, J Du, Y Wang, P Zheng… - Journal of …, 2022 - liebertpub.com
Gastrointestinal dysfunction is a common peripheral organ complication after traumatic brain
injury (TBI), yet the underlying mechanism remains unknown. TBI has been demonstrated to …

Translocation and dissemination of gut bacteria after severe traumatic brain injury

W Yang, Q Yuan, Z Li, Z Du, G Wu, J Yu, J Hu - Microorganisms, 2022 - mdpi.com
Enterobacteriaceae are often found in the lungs of patients with severe Traumatic Brain
Injury (sTBI). However, it is unknown whether these bacteria come from the gut microbiota …

[HTML][HTML] Inulin supplementation prior to mild traumatic brain injury mitigates gut dysbiosis, and brain vascular and white matter deficits in mice

LM Yanckello, YH Chang, MK Sun, G Chlipala… - Frontiers in …, 2022 - frontiersin.org
Mild traumatic brain injury (mTBI) has been shown to negatively alter bacterial diversity and
composition within the gut, known as dysbiosis, in rodents and humans. These changes …

The association of traumatic brain injury, gut microbiota and the corresponding metabolites in mice

S Wang, K Zhu, X Hou, L Hou - Brain research, 2021 - Elsevier
Abstract Background Traumatic Brain Injury (TBI) present a significant burden to global
health. Close association and mutual regulation exist between the brain and gut microbiota …

[HTML][HTML] Lactobacillus acidophilus exerts neuroprotective effects in mice with traumatic brain injury

Y Ma, T Liu, J Fu, S Fu, C Hu, B Sun, X Fan, J Zhu - The Journal of Nutrition, 2019 - Elsevier
Background Traumatic brain injury (TBI) causes dysbiosis and intestinal barrier disruption,
which further exacerbate brain damage via an inflammatory pathway. Gut microbiota …

Gut microbiota and acute central nervous system injury: a new target for therapeutic intervention

B Yuan, X Lu, Q Wu - Frontiers in immunology, 2021 - frontiersin.org
Acute central nervous system (CNS) injuries, including stroke, traumatic brain injury (TBI),
and spinal cord injury (SCI), are the common causes of death or lifelong disabilities …

Investigating alterations in caecum microbiota after traumatic brain injury in mice

L Wen, W You, Y Wang, Y Zhu, H Wang… - JoVE (Journal of …, 2019 - jove.com
Increasing evidence shows that the microbiota-gut-brain axis plays an important role in the
pathogenesis of brain diseases. Several studies also demonstrate that traumatic brain …

Fecal microbiota transplantation inhibited neuroinflammation of traumatic brain injury in mice via regulating the gut–brain axis

X Hu, H Jin, S Yuan, T Ye, Z Chen, Y Kong… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction Recent studies have highlighted the vital role of gut microbiota in traumatic
brain injury (TBI). Fecal microbiota transplantation (FMT) is an effective means of regulating …