Immunomodulatory potential of flavonoids for the treatment of autoimmune diseases and tumour

L Han, Q Fu, C Deng, L Luo, T Xiang… - … Journal of Immunology, 2022 - Wiley Online Library
The immune system plays an indispensable role in maintaining human health against the
invasion of foreign materials, microorgainisms and pathogens. The autoimmune diseases …

Effects of flavonoids and its derivatives on immune cell responses

G Martínez, MR Mijares… - Recent Patents on …, 2019 - ingentaconnect.com
Background: Various pieces of evidence have shown that people who consume foods rich in
polyphenolic and flavonoids compounds have a lower incidence of inflammatory …

The role of flavonoids in autoimmune diseases: Therapeutic updates

KRR Rengasamy, H Khan, S Gowrishankar… - Pharmacology & …, 2019 - Elsevier
Flavonoids are natural polyphenolic compounds which are included in a panoply of drugs
and used to treat and/or manage human ailments such as metabolic, cardiovascular …

Immunomodulatory effects of flavonoids: possible induction of T CD4+ regulatory cells through suppression of mTOR pathway signaling activity

A Hosseinzade, O Sadeghi… - Frontiers in …, 2019 - frontiersin.org
The increasing rate of autoimmune disorders and cancer in recent years has been a
controversial issue in all aspects of prevention, diagnosis, prognosis and treatment. Among …

Naturally occurring immunomodulators with antitumor activity: An insight on their mechanisms of action

SIA Mohamed, I Jantan, MA Haque - International Immunopharmacology, 2017 - Elsevier
Natural products with immunomodulatory activity are widely used in treatment of many
diseases including autoimmune diseases, inflammatory disorders in addition to cancer …

Flavonoids regulate tumor-associated macrophages–from structure-activity relationship to clinical potential

Q Sun, Q Liu, X Zhou, X Wang, H Li, W Zhang… - Pharmacological …, 2022 - Elsevier
In recent years, the strategy for tumor therapy has changed from focusing on the direct killing
effect of different types of therapeutic agents on cancer cells to the new mainstream of multi …

Flavonoids as cytokine modulators: a possible therapy for inflammation-related diseases

N Leyva-López, EP Gutierrez-Grijalva… - International journal of …, 2016 - mdpi.com
High levels of cytokines, such as interleukin (IL)-1β, tumor necrosis factor (TNF)-α and IL-6,
are associated with chronic diseases like rheumatoid arthritis, asthma, atherosclerosis …

Flavonoids, inflammation and immune system

FJ Pérez-Cano, M Castell - Nutrients, 2016 - mdpi.com
Flavonoids, including around 6000 phenolic compounds, are products of the secondary
metabolism of plants which can be a part of one's diet via the consumption of many edible …

Polyphenols affect the humoral response in cancer, infectious and allergic diseases and autoimmunity by modulating the activity of TH1 and TH2 cells

M Benvenuto, C Focaccetti, S Ciuffa, S Fazi… - Current Opinion in …, 2021 - Elsevier
Polyphenols are a wide class of natural substances, pleiotropic molecules capable of
modulating several processes, involved in the humoral and cellular immune response. The …

[HTML][HTML] Natural products as targeted modulators of the immune system

K Wang, M Conlon, W Ren, BB Chen… - Journal of Immunology …, 2018 - ncbi.nlm.nih.gov
For decades, compounds derived from natural products have demonstrated their
effectiveness as therapeutic agents in different areas, such as metabolic disorder …