New RNA-based breakthroughs in Alzheimer's disease diagnosis and therapeutics

M Riscado, B Baptista, F Sousa - Pharmaceutics, 2021 - mdpi.com
Dementia is described as the fifth leading cause of death worldwide and Alzheimer's
disease (AD) is recognized as the most common, causing a huge impact on health costs and …

Non-coding RNAs involved in the molecular pathology of Alzheimer's disease: a systematic review

RJ Canoy, JC Sy, CD Deguit, CB Castro… - Frontiers in …, 2024 - frontiersin.org
Alzheimer's disease (AD) is the leading cause of dementia globally, having a
pathophysiology that is complex and multifactorial. Recent findings highlight the significant …

Molecular Research on Alzheimer's Disease

L Falsetti - Biomedicines, 2023 - mdpi.com
Alzheimer's disease (AD) is the most common form of dementia worldwide. Despite its
prevalence and incidence, there are few and limited specific treatments for this disabling …

The role of non-coding RNAs in Alzheimer's disease: from regulated mechanism to therapeutic targets and diagnostic biomarkers

Y Zhang, Y Zhao, X Ao, W Yu, L Zhang… - Frontiers in aging …, 2021 - frontiersin.org
Alzheimer's disease (AD) is a progressive neurodegenerative disorder. AD is characterized
by the production and aggregation of beta-amyloid (Aβ) peptides, hyperphosphorylated tau …

[HTML][HTML] Insights into the mechanisms of non-coding RNAs' implication in the pathogenesis of Alzheimer's disease

M Khodayi-Shahrak, M Khalaj-Kondori, MAH Feizi… - EXCLI …, 2022 - ncbi.nlm.nih.gov
Non-coding RNAs including long non-coding RNAs (lncRNAs) and microRNAs (miRNAs)
are implicated in the regulation of gene expression at transcriptional, posttranscriptional …

A signature of five long non-coding RNAs for predicting the prognosis of Alzheimer's disease based on competing endogenous RNA networks

C Huaying, J Xing, J Luya, N Linhui, S Di… - Frontiers in aging …, 2021 - frontiersin.org
Long non-coding RNAs (lncRNAs) play important roles in the pathogenesis of Alzheimer's
disease (AD). However, the functions and regulatory mechanisms of lncRNA are largely …

Noncoding RNAs in Alzheimer's disease

ML Idda, R Munk, K Abdelmohsen… - Wiley Interdisciplinary …, 2018 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the main cause
of dementia among the elderly worldwide. Despite intense efforts to develop drugs for …

[图书][B] Biological, Diagnostic and Therapeutic Advances in Alzheimer's Disease

GM Ashraf, A Alexiou - 2019 - Springer
Alzheimer's disease (AD) is still a hardly curable disease with several symptoms of
behavioral and cognitive impairments. Besides the altered protein levels and the side effects …

Alzheimer's disease and ncRNAs

R Maoz, BP Garfinkel, H Soreq - Neuroepigenomics in aging and disease, 2017 - Springer
Alzheimer's disease is a devastating neurodegenerative disorder affecting a significant
portion of the world's rapidly growing aging population. In spite of its prevalence, the etiology …

The long non-coding RNAs in neurodegenerative diseases: novel mechanisms of pathogenesis

P Riva, A Ratti, M Venturin - Current Alzheimer Research, 2016 - ingentaconnect.com
Background: Long-non-coding RNAs (lncRNAs), RNA molecules longer than 200
nucleotides, have been involved in several biological processes and in a growing number of …