Long‐term outcomes of BRCA1/BRCA2 testing: risk reduction and surveillance

MD Schwartz, C Isaacs, KD Graves, E Poggi… - Cancer, 2012 - Wiley Online Library
Abstract BACKGROUND: For BRCA1/BRCA2 gene testing to benefit public health, mutation
carriers must initiate appropriate risk management strategies. There has been little research …

Association between clinical characteristics and risk‐reduction interventions in women who underwent BRCA1 and BRCA2 testing: A single‐institution study

A Uyei, SK Peterson, J Erlichman, K Broglio, S Yekell… - Cancer, 2006 - Wiley Online Library
BACKGROUND. Women who are at increased risk for breast and ovarian cancers,
especially BRCA1 and BRCA2 mutation carriers, face a myriad of risk‐reduction options …

Long-Term Psychosocial Outcomes of BRCA1/BRCA2 Testing: Differences across Affected Status and Risk-Reducing Surgery Choice

KD Graves, P Vegella, EA Poggi, BN Peshkin… - … Biomarkers & Prevention, 2012 - AACR
Background: Numerous studies have documented the short-term impact of BRCA1/BRCA2
(BRCA1/2) testing; however, little research has examined the long-term impact of testing. We …

Genetic testing for a BRCA1 mutation: Prophylactic surgery and screening behavior in women 2 years post testing

JR Botkin, KR Smith, RT Croyle, BJ Baty… - American journal of …, 2003 - Wiley Online Library
Mutations in the BRCA1 gene are associated with an increased risk of breast and ovarian
cancer in carrier women. An understanding of behavioral responses to BRCA1 mutation …

Factors Associated with Decisions about Clinical BRCA1/2 Testing

K Armstrong, K Calzone, J Stopfer, G Fitzgerald… - … Biomarkers & Prevention, 2000 - AACR
Testing for mutations in BRCA1 and BRCA2 can provide important information about breast
and ovarian cancer risk to a small but identifiable subgroup of women. Women who test …

Awareness and utilization of BRCA1/2 testing among US primary care physicians

CA Bellcross, K Kolor, KAB Goddard, RJ Coates… - American journal of …, 2011 - Elsevier
BACKGROUND: Testing for mutations in the breast and ovarian cancer susceptibility genes
BRCA1 and BRCA2 (BRCA) has been commercially available since 1996. PURPOSE: This …

Utilization of Screening and Preventive Surgery Among Unaffected Carriers of a BRCA1 or BRCA2 Gene Mutation

S Wainberg, J Husted - Cancer Epidemiology Biomarkers & Prevention, 2004 - AACR
Objective: Women who are carriers of BRCA gene mutations have an elevated lifetime risk
of developing breast or ovarian cancer. Although a number of risk-reducing options are …

Bilateral Prophylactic Oophorectomy and Ovarian Cancer Screening Following BRCA1/BRCA2 Mutation Testing

MD Schwartz, E Kaufman, BN Peshkin… - Journal of Clinical …, 2003 - ascopubs.org
Purpose: Despite the widespread availability of genetic testing for BRCA1/BRCA2
mutations, little is known about the impact of testing on ovarian cancer prevention and …

Prophylactic surgery decisions and surveillance practices one year following BRCA1/2 testing

C Lerman, C Hughes, RT Croyle, D Main, C Durham… - Preventive …, 2000 - Elsevier
Background. Although genetic testing for breast cancer risk is clinically available, its impact
on health-related behaviors is unknown. This study examined prophylactic surgery and …

Utilization of Breast Cancer Screening in a Clinically Based Sample of Women after BRCA1/2 Testing

BN Peshkin, MD Schwartz, C Isaacs, C Hughes… - … Biomarkers & Prevention, 2002 - AACR
We conducted a prospective, observational study to determine breast cancer screening
practices among self-referred high-risk women who pursued genetic testing for BRCA1 and …