A central goal in neuroscience is to determine how the brain's neuronal circuits generate
perception, cognition and emotions and how these lead to appropriate behavioural actions …

Highlights•Genetically encoded voltage indicators (GEVIs) come of age.•GEVIs overcome
limitations of current voltage sensitive dyes.•Two main classes of GEVIs have been …

A longstanding goal in neuroscience is to understand how spatiotemporal patterns of
neuronal electrical activity underlie brain function, from sensory representations to decision …

Understanding of the cellular mechanisms underlying brain functions such as cognition and
emotions requires monitoring of membrane voltage at the cellular, circuit, and system levels …

Imaging voltage using fluorescent-based sensors could be an ideal technique to probe
neural circuits with high spatiotemporal resolution. However, due to insufficient signal-to …

Genetically encoded voltage indicators (GEVIs) hold immense potential for monitoring
neuronal population activity. To date, best-in-class GEVIs rely on one-photon excitation …

Genetically encoded voltage indicators (GEVIs) enable monitoring of neuronal activity at
high spatial and temporal resolution. However, the utility of existing GEVIs has been limited …

Genetically encoded voltage indicators (GEVIs) are a promising technology for fluorescence
readout of millisecond-scale neuronal dynamics. Previous GEVIs had insufficient signaling …

Genetically encoded voltage indicators (GEVIs) promise to reveal the membrane potential of
genetically targeted neuronal populations through noninvasive, chronic imaging of large …

Widefield imaging with genetically encoded voltage indicators (GEVIs) is a promising
approach for understanding the role of large cortical networks in the neural coding of …