Artemisinin–second career as anticancer drug?

T Efferth - World Journal of Traditional Chinese Medicine, 2015 - journals.lww.com
Artemisinin represents a showcase example not only for the activity of medicinal herbs
deriving from traditional chinese medicine, but for phytotherapy in general. Its isolation from …

Artemisinin and its derivatives: A promising cancer therapy

BH Kiani, WK Kayani, AU Khayam, E Dilshad… - Molecular Biology …, 2020 - Springer
The world is experiencing a cancer epidemic and an increase in the prevalence of the
disease. Cancer remains a major killer, accounting for more than half a million deaths …

From ancient herb to modern drug: Artemisia annua and artemisinin for cancer therapy

T Efferth - Seminars in cancer biology, 2017 - Elsevier
Artemisia annua L. is used throughout Asia and Africa as tea and press juice to treat malaria
and related symptomes (fever, chills). Its active ingredient, artemisinin (ARS), has been …

Antitumor research on artemisinin and its bioactive derivatives

Y Zhang, G Xu, S Zhang, D Wang… - Natural products and …, 2018 - Springer
Cancer is the leading cause of human death which seriously threatens human life. The
antimalarial drug artemisinin and its derivatives have been discovered with considerable …

Artemisinins as anticancer drugs: Novel therapeutic approaches, molecular mechanisms, and clinical trials

C Xu, H Zhang, L Mu, X Yang - Frontiers in Pharmacology, 2020 - frontiersin.org
Artemisinin and its derivatives have shown broad-spectrum antitumor activities in vitro and in
vivo. Furthermore, outcomes from a limited number of clinical trials provide encouraging …

Molecular pharmacology and pharmacogenomics of artemisinin and its derivatives in cancer cells

T Efferth - Current drug targets, 2006 - ingentaconnect.com
Secondary metabolites from plants can serve as defense against herbivores, microbes,
viruses or competing plants. Many compounds from medicinal plants have pharmacological …

A comprehensive overview of Artemisinin and its derivatives as anticancer agents

Z Zeng, D Chen, L Chen, B He, Y Li - European Journal of Medicinal …, 2023 - Elsevier
Artemisinin is the crucial ingredient of artemisia annua, a traditional Chinese medicine used
for the therapy of malaria in China for hundreds of years. In recent years, the anticancer …

Artemisinin and its derivatives as a repurposing anticancer agent: what else do we need to do?

Z Li, Q Li, J Wu, M Wang, J Yu - Molecules, 2016 - mdpi.com
Preclinical investigation and clinical experience have provided evidence on the potential
anticancer effect of artemisinin and its derivatives (ARTs) in the recent two decades. The …

[PDF][PDF] Artemisia annua (Qinghao): a pharmacological review

S Das - International journal of pharmaceutical sciences and …, 2012 - Citeseer
Artemisia annua L., also known as sweet wormwood, sweet annie, sweet sagewort and
annual wormwood (Chinese: qngho), is a common type of wormwood that is native to …

Anticancer activities of artemisinin and its bioactive derivatives

GL Firestone, SN Sundar - Expert reviews in molecular medicine, 2009 - cambridge.org
Artemisinin, a sesquiterpene lactone derived from the sweet wormwood plant Artemisia
annua, and its bioactive derivatives exhibit potent anticancer effects in a variety of human …