Embryonic chromosomal aneuploidies are the major genetic cause of infertility in humans.
As a result, preimplantation genetic diagnosis for aneuploidy (PGT-A) has emerged as a …

Objective Preimplantation genetic testing for Aneuploidies (PGT-A) has been performed to
screen embryos for nearly three decades. For certain patient populations, the selection of …

Chromosomal abnormalities are extremely common in human preimplantation embryos,
affecting the majority of blastocysts produced by women in their late thirties and forties. It has …

Abstract Treatment for many infertile couples often consists of in vitro fertilization (IVF) but an
estimated 70% of IVF cycles fail to produce a live birth. In an attempt to improve the live birth …

Objective Preimplantation genetic testing for aneuploidies (PGT-A) has been introduced into
clinical practice to improve outcomes. However, diagnostic accuracy remains controversial …

While chromosomal mosaicism in the embryo was observed already in the '90s using both
karyotyping and FISH technologies, the full extent of this phenomenon and the overall …

Study question Is it possible to predict an euploid chromosomal constitution from RNA-Seq
data and identify a transcriptomic profile compatible with extended embryonic development …

OBJECTIVE Preimplantation genetic testing for aneuploidies (PGT-A) aims to improve
clinical outcomes. However, diagnostic accuracy remains a concern, particularly when …

Aneuploidy in preimplantation embryos is a major cause of human reproductive failure.
Unlike uniformly aneuploid embryos, embryos diagnosed as diploid-aneuploid mosaics after …

Introduction In the context of IVF, it has become imperative to emphasize on embryo
evaluation in order to maximise assisted conception outcome while minimising the risk of …