Healthy aging is associated with decreased neural selectivity (dedifferentiation) in category-
selective cortical regions. This finding has prompted the suggestion that dedifferentiation …

Dedifferentiation, or decreased processing specificity, has been suggested to represent a
ubiquitous characteristic of cognitive aging. In this study, we examined both age-related …

This review focuses on possible contributions of neural dedifferentiation to age-related
cognitive decline. Neural dedifferentiation is held to reflect a breakdown in the functional …

There is widespread evidence that memory deteriorates with aging, however the exact
mechanisms that underlie these changes are not well understood. Given the growing size of …

Current theories of cognitive aging argue that neural representations become less distinctive
in old age, a phenomenon known as dedifferentiation. The present study used multi-voxel …

While aging is generally associated with episodic memory decline, not all older adults
exhibit memory loss. Furthermore, emotional memories are not subject to the same extent of …

Working memory function declines across the lifespan. Computational models of aging
attribute such memory impairments to reduced distinctiveness between neural …

Age-related neural dedifferentiation—a decline in the distinctiveness of neural
representations in the aging brain—has been associated with age-related declines in …

Many cognitive abilities decline with age even in the absence of detectable pathology.
Recent evidence indicates that age-related neural dedifferentiation, operationalized in terms …

It is well established that brain structures and cognitive functions change across the life
span. A long-standing hypothesis called “age differentiation” additionally posits that the …