Background Deep brain stimulation (DBS) of the subcallosal cingulate white matter has
shown promise as an intervention for patients with chronic, unremitting depression. To test …

Background Stimulation adjustment is required to optimise outcomes of deep brain
stimulation (DBS) for treatment-resistant depression, but controlled data for ideal stimulation …

Objective: Deep brain stimulation of the subcallosal cingulate (SCC DBS) has been studied
as a potential treatment for severe and refractory major depressive disorder since 2005. The …

Background: Deep brain stimulation (DBS) of the subcallosal cingulate (SCC) is reported to
be a safe and effective new treatment for treatment-resistant depression (TRD). However …

Background: To date, antidepressant drugs show limited efficacy, leaving a large number of
patients experiencing severe and persistent symptoms of major depression. Previous open …

Object Deep brain stimulation (DBS) has been recently investigated as a treatment for major
depression. One of the proposed targets for this application is the subcallosal cingulate …

Context Deep brain stimulation (DBS) may be an effective intervention for treatment-resistant
depression (TRD), but available data are limited. Objective To assess the efficacy and safety …

Background Deep brain stimulation (DBS) of the subcallosal cingulate gyrus (SCG) is an
experimental approach in treatment-resistant depression (TRD). Short-term results of …

Background Deep brain stimulation (DBS) applied to the subgenual cingulate cortex (SCC)
has been recently investigated as a potential treatment for severe and chronic treatment …

Deep brain stimulation (DBS) is currently tested as an experimental therapy for patients with
treatment-resistant depression (TRD). Here we report on the short-and long-term (1 yr) …