Neutrophils efficiently cross-prime naive T cells in vivo

C Beauvillain, Y Delneste, M Scotet… - Blood, The Journal …, 2007 - ashpublications.org
Neutrophils are professional phagocytes that migrate early, in high number, to the infection
sites. Our study has analyzed how neutrophils cross-present antigens and influence CD8+ T …

Microbe-specific unconventional T cells induce human neutrophil differentiation into antigen cross-presenting cells

MS Davey, MP Morgan, AR Liuzzi, CJ Tyler… - The Journal of …, 2014 - journals.aai.org
The early immune response to microbes is dominated by the recruitment of neutrophils
whose primary function is to clear invading pathogens. However, there is emerging …

[HTML][HTML] Murine neutrophils present Class II restricted antigen

S Culshaw, OR Millington, JM Brewer, IB McInnes - Immunology letters, 2008 - Elsevier
Neutrophils were originally described as short lived, terminally differentiated phagocytes that
contribute only to the innate immune response. Recent evidence of neutrophil cytokine …

Neutrophils acquire the capacity for antigen presentation to memory CD4+ T cells in vitro and ex vivo

M Vono, A Lin, A Norrby-Teglund… - Blood, The Journal …, 2017 - ashpublications.org
Neutrophils are critical cells of the innate immune system and rapidly respond to tissue
injury and infection. Increasing evidence also indicates that neutrophils have versatile …

Polymorphonuclear neutrophils as accessory cells for T‐cell activation: major histocompatibility complex class II restricted antigen‐dependent induction of T‐cell …

M Radsak, C Iking‐Konert, S Stegmaier… - …, 2000 - Wiley Online Library
Polymophonuclear cells (PMN) of healthy donors do not express major histocompatibility
complex (MHC) class II antigens or the T‐cell costimulatory molecules CD80 or CD86 …

Neutrophil involvement in cross-priming CD8+ T cell responses to bacterial antigens

AR Tvinnereim, SE Hamilton, JT Harty - The Journal of Immunology, 2004 - journals.aai.org
Substantial CD8+ T cell responses are generated after infection of mice with recombinant
Listeria monocytogenes strains expressing a model epitope (lymphocytic choriomeningitis …

Activation of human T cells by major histocompatability complex class II expressing neutrophils: proliferation in the presence of superantigen, but not tetanus toxoid

NA Fanger, C Liu, PM Guyre… - Blood, The Journal …, 1997 - ashpublications.org
The primary function of polymorphonuclear neutrophils (PMN) in the immune response
appears to be acute phagocytic clearance of foreign pathogens and release of inflammatory …

Mouse neutrophils are professional antigen-presenting cells programmed to instruct Th1 and Th17 T-cell differentiation

DS Abi Abdallah, CE Egan, BA Butcher… - International …, 2011 - academic.oup.com
Neutrophils play a major role in the innate immune system and are normally considered to
be short-lived effector cells that exert anti-microbial activity and sometimes …

The outcome of neutrophil-T cell contact differs depending on activation status of both cell types

D Minns, KJ Smith, G Hardisty, AG Rossi… - Frontiers in …, 2021 - frontiersin.org
Neutrophils and T cells exist in close proximity in lymph nodes and inflamed tissues during
health and disease. They are able to form stable interactions, with profound effects on the …

Neutrophil differentiation into a unique hybrid population exhibiting dual phenotype and functionality of neutrophils and dendritic cells

H Matsushima, S Geng, R Lu… - Blood, The Journal …, 2013 - ashpublications.org
Neutrophils have been reported to acquire surface expression of MHC class II and co-
stimulatory molecules as well as T-cell stimulatory activities when cultured with selected …